idUS - Perfil del autor: Valle Rosado, Iván

Autorice su foto

Nombre	Valle Rosado, Iván
Departamento	Genética
Área de conocimiento	Genética
Categoría profesional	Profesor Contratado Doctor
Correo electrónico	Solicitar

Nº publicaciones

19
Nº visitas

1930
Nº descargas

1466

Tipología

Orden

Publicaciones
Artículo Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions Medrano, M.; Contreras, M.; Caballero Velázquez, Teresa; Martínez, L.; Bejarano-García, J. A.; Calderón Ruiz, Rocío; García-Calderón, C. B.; Valle Rosado, Iván; Pérez Simón, José Antonio (Nature Publishing Group, 2024) BACKGROUND: Several studies have described a potential anti-tumour effect of cannabinoids (CNB). CNB receptor 2 (CB2) is ...
Tesis Doctoral Uso de cannabinoides para el tratamiento de hemopatías malignas Medrano Domínguez, María Teresa; Pérez Simón, José Antonio; Valle Rosado, Iván (2023) Aunque el sistema hematopoyético e inmunológico muestran altos niveles del receptor cannabinoide CB2, el efecto de los ...
Artículo A novel biocompatible polymer derived from D-mannitol used as a vector in the field of genetic engineering of eukaryotic cells Pérez, David; Moyá Morán, María Luisa; Bautista, María; León, Rosa; Molina-Márquez, Ana; Vila, Marta; Romero Azogil, Lucía; Benito Hernández, Elena María; García Martín, María de Gracia; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; López-Cornejo, María del Pilar (Elsevier Science BV, 2023) The design and preparation of new vectors to transport genetic material and increase the transfection efficiency continue ...
Tesis Doctoral Contribución de la ruta de reparación del ADN Anemia de Fanconi al mantenimiento de la estabilidad de la horquilla de replicación durante la incorporación de desoxirribonucleótidos hidroximetilados Moreno Gordillo, Paula; Valle Rosado, Iván (2023) El genoma está constantemente expuesto a agentes tanto endógenos como exógenos que amenazan la integridad del mismo. Es ...
Capítulo de Libro Innovación docente en las prácticas de laboratorio de genética: clase invertida y pensamiento crítico Castellano Pozo, Maikel; Iglesias Sigüenza, Francisco Javier; Comaills, Valentine; Valle Rosado, Iván (Dykinson, 2023)
Artículo Fluorescent calixarene-schiff as a nanovehicle with biomedical purposes Lebrón Romero, José Antonio; Moyá Morán, María Luisa; López López, Manuel; Deasy, M.; Muñoz Wic, Ana; García Calderón, Clara Beatriz; Valle Rosado, Iván; Bernal Pérez, Eva; Ostos Marcos, Francisco José; López-Cornejo, María del Pilar (Multidisciplinary Digital Publishing Institute (MDPI), 2022) Gene therapy is a technique that is currently under expansion and development. Recent advances in genetic medicine have ...
Artículo XRCC1 Prevents Replication Fork Instability during Misincorporation of the DNA Demethylation Bases 5-Hydroxymethyl-2′-Deoxycytidine and 5-Hydroxymethyl-2′-Deoxyuridine Peña Gómez, Mª José; Suárez Pizarro, Marina; Valle Rosado, Iván (MDPI, 2022) Whilst avoidance of chemical modifications of DNA bases is essential to maintain genome stability, during evolution ...
Trabajo Fin de Máster Evaluating the modulation of the intracellular production of H2S in the functionality and metabolic activity of primary cultures of pancreatic islets Pino Pérez, Inmaculada; Martín-Montalvo Sánchez, Alejandro; Valle Rosado, Iván (2022) Diabetes Mellitus is a metabolic disease characterized by hyperglycaemia that currently affects one in ten people worldwide. ...
Artículo FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2’-deoxycytidine and 5-hydroxymethyl-2’-deoxyuridine Peña Gómez, Mª José; Moreno Gordillo, Paula; Narmonté, Milda; García Calderón, Clara Beatriz; Ruksenaité, Audronė; Klimašauskas, Saulius; Valle Rosado, Iván (Springer Nature, 2022) Fanconi anemia (FA) is a rare hereditary disorder caused by mutations in any one of the FANC genes. FA cells are mainly ...
Artículo Multivalent Calixarene-Based Liposomes as Platforms for Gene and Drug Delivery Lebrón Romero, José Antonio; López López, Manuel; García Calderón, Clara Beatriz; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; Rodik, Roman V; Kalchenko, Vitaly I.; Bernal Pérez, Eva; Moyá Morán, María Luisa; López-Cornejo, María del Pilar; Ostos Marcos, Francisco José (MDPI, 2021) The formation of calixarene-based liposomes was investigated, and the characterization of these nanostructures was carried ...
Artículo Metallo-Liposomes Derived from the [Ru(bpy)3]2+ Complex as Nanocarriers of Therapeutic Agents Moyá Morán, María Luisa; Ostos Marcos, Francisco José; Moreno, Izamar; García, Diandra; Moreno Gordillo, Paula; Valle Rosado, Iván; López-Cornejo, María del Pilar; Lebrón Romero, José Antonio; López López, Manuel (Multidisciplinary Digital Publishing Institute, 2021) The obtaining of nanocarriers of gene material and small drugs is still an interesting research line. Side-effects produced ...
Artículo A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae Rodríguez Galán, Olga; García Gómez, Juan José; Valle Rosado, Iván; Wei, Wu; Méndez-Godoy, Alfonso; Pillet, Benjamin; Alekseenko, Alisa; Steinmetz, Lars M.; Pelechano, Vicent; Kressler, Dieter; Cruz Díaz, Jesús de la (Oxford University Press, 2021) Proteostasis needs to be tightly controlled to meet the cellular demand for correctly de novo folded proteins and to avoid ...
Artículo Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material Lebrón Romero, José Antonio; Ostos Marcos, Francisco José; López López, Manuel; Moyá Morán, María Luisa; Sales, Carlos; García, Encarnación; García Calderón, Clara Beatriz; García Calderón, Margarita; Peña Gómez, Mª José; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; López-Cornejo, María del Pilar (MDPI, 2020) Gene therapy is a therapeutic process consisting of the transport of genetic material into cells. The design and preparation ...
Artículo Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletion Bejarano García, José Antonio; Millán-Uclés, África; Valle Rosado, Iván; Sánchez Abarca, Luis Ignacio; Caballero Velázquez, Teresa; Durán Galván, María José; Pérez Simón, José Antonio; Piraut Palomo, José Ignacio (2016) It is established that hematopoietic stem cells (HSC) in the hypoxic bone marrow have adapted their metabolism to ...
Artículo Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium Pontel, Lucas B.; Langenick, Judith; Valle Rosado, Iván; Zhang, Xiao-Yin; Traynor, David; Kay, Robert R.; Patel, Ketan J. (The Company of Biologists, 2016) As time passes, mutations accumulate in the genomes of all living organisms. These changes promote genetic diversity, but ...
Artículo Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen Pontel, Lucas B.; Valle Rosado, Iván; Burgos Barragán, Guillermo; Garaycoechea, Juan I.; Yu, Rui; Arends, Mark J.; Patel, Ketan J. (Cell Press, 2015) Endogenous formaldehyde is produced by numerous biochemical pathways fundamental to life, and it can crosslink both DNA ...
Artículo Final pre-40s maturation depends on the functional integrity of the 60s subunit ribosomal protein l3 García Gómez, Juan José; Fernández Pevida, Antonio; Lebaron, Simon; Valle Rosado, Iván; Tollervey, David W.; Kressler, Dieter; Cruz Díaz, Jesús de la (Public Library of Science, 2014) Ribosomal protein L3 is an evolutionarily conserved protein that participates in the assembly of early pre-60S particles. ...
Artículo Functional analysis of saccharomyces cerevisiae ribosomal protein Rpl3p in ribosome synthesis Valle Rosado, Iván; Kressler, Dieter; Cruz Díaz, Jesús de la (Oxford University Press, 2007) Ribosome synthesis in eukaryotes requires a multitude oftrans-acting factors. These factors act at many steps as the ...
Artículo Npa1p is an essential trans-acting factor required for an early step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae Valle Rosado, Iván; Cruz Díaz, Jesús de la (Cold Spring Harbor Laboratory Press, 2004) Ribosome biogenesis requires > 100 nonribosomal proteins, which are associated with different preribosomal particles. The ...