NameValle Rosado, Iván
DepartmentGenética
Knowledge areaGenética
Professional categoryProfesor Contratado Doctor
E-mailRequest
           
  • No. publications

    19

  • No. visits

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  • No. downloads

    1450


 

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Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions

Medrano, M.; Contreras, M.; Caballero Velázquez, Teresa; Martínez, L.; Bejarano-García, J. A.; Calderón Ruiz, Rocío; García-Calderón, C. B.; Valle Rosado, Iván; Pérez Simón, José Antonio (Nature Publishing Group, 2024)
BACKGROUND: Several studies have described a potential anti-tumour effect of cannabinoids (CNB). CNB receptor 2 (CB2) is ...
PhD Thesis
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Uso de cannabinoides para el tratamiento de hemopatías malignas

Medrano Domínguez, María Teresa; Pérez Simón, José Antonio; Valle Rosado, Iván (2023)
Aunque el sistema hematopoyético e inmunológico muestran altos niveles del receptor cannabinoide CB2, el efecto de los ...
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A novel biocompatible polymer derived from D-mannitol used as a vector in the field of genetic engineering of eukaryotic cells

Pérez, David; Moyá Morán, María Luisa; Bautista, María; León, Rosa; Molina-Márquez, Ana; Vila, Marta; Romero Azogil, Lucía; Benito Hernández, Elena María; García Martín, María de Gracia; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; López-Cornejo, María del Pilar (Elsevier Science BV, 2023)
The design and preparation of new vectors to transport genetic material and increase the transfection efficiency continue ...
PhD Thesis
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Contribución de la ruta de reparación del ADN Anemia de Fanconi al mantenimiento de la estabilidad de la horquilla de replicación durante la incorporación de desoxirribonucleótidos hidroximetilados

Moreno Gordillo, Paula; Valle Rosado, Iván (2023)
El genoma está constantemente expuesto a agentes tanto endógenos como exógenos que amenazan la integridad del mismo. Es ...
Chapter of Book
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Innovación docente en las prácticas de laboratorio de genética: clase invertida y pensamiento crítico

Castellano Pozo, Maikel; Iglesias Sigüenza, Francisco Javier; Comaills, Valentine; Valle Rosado, Iván (Dykinson, 2023)
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Fluorescent calixarene-schiff as a nanovehicle with biomedical purposes

Lebrón Romero, José Antonio; Moyá Morán, María Luisa; López López, Manuel; Deasy, M.; Muñoz Wic, Ana; García Calderón, Clara Beatriz; Valle Rosado, Iván; Bernal Pérez, Eva; Ostos Marcos, Francisco José; López-Cornejo, María del Pilar (Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Gene therapy is a technique that is currently under expansion and development. Recent advances in genetic medicine have ...
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XRCC1 Prevents Replication Fork Instability during Misincorporation of the DNA Demethylation Bases 5-Hydroxymethyl-2′-Deoxycytidine and 5-Hydroxymethyl-2′-Deoxyuridine

Peña Gómez, Mª José; Suárez Pizarro, Marina; Valle Rosado, Iván (MDPI, 2022)
Whilst avoidance of chemical modifications of DNA bases is essential to maintain genome stability, during evolution ...
Master's Final Project
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Evaluating the modulation of the intracellular production of H2S in the functionality and metabolic activity of primary cultures of pancreatic islets

Pino Pérez, Inmaculada; Martín-Montalvo Sánchez, Alejandro; Valle Rosado, Iván (2022)
Diabetes Mellitus is a metabolic disease characterized by hyperglycaemia that currently affects one in ten people worldwide. ...
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FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2’-deoxycytidine and 5-hydroxymethyl-2’-deoxyuridine

Peña Gómez, Mª José; Moreno Gordillo, Paula; Narmonté, Milda; García Calderón, Clara Beatriz; Ruksenaité, Audronė; Klimašauskas, Saulius; Valle Rosado, Iván (Springer Nature, 2022)
Fanconi anemia (FA) is a rare hereditary disorder caused by mutations in any one of the FANC genes. FA cells are mainly ...
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Multivalent Calixarene-Based Liposomes as Platforms for Gene and Drug Delivery

Lebrón Romero, José Antonio; López López, Manuel; García Calderón, Clara Beatriz; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; Rodik, Roman V; Kalchenko, Vitaly I.; Bernal Pérez, Eva; Moyá Morán, María Luisa; López-Cornejo, María del Pilar; Ostos Marcos, Francisco José (MDPI, 2021)
The formation of calixarene-based liposomes was investigated, and the characterization of these nanostructures was carried ...
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Metallo-Liposomes Derived from the [Ru(bpy)3]2+ Complex as Nanocarriers of Therapeutic Agents

Moyá Morán, María Luisa; Ostos Marcos, Francisco José; Moreno, Izamar; García, Diandra; Moreno Gordillo, Paula; Valle Rosado, Iván; López-Cornejo, María del Pilar; Lebrón Romero, José Antonio; López López, Manuel (Multidisciplinary Digital Publishing Institute, 2021)
The obtaining of nanocarriers of gene material and small drugs is still an interesting research line. Side-effects produced ...
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A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae

Rodríguez Galán, Olga; García Gómez, Juan José; Valle Rosado, Iván; Wei, Wu; Méndez-Godoy, Alfonso; Pillet, Benjamin; Alekseenko, Alisa; Steinmetz, Lars M.; Pelechano, Vicent; Kressler, Dieter; Cruz Díaz, Jesús de la (Oxford University Press, 2021)
Proteostasis needs to be tightly controlled to meet the cellular demand for correctly de novo folded proteins and to avoid ...
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Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material

Lebrón Romero, José Antonio; Ostos Marcos, Francisco José; López López, Manuel; Moyá Morán, María Luisa; Sales, Carlos; García, Encarnación; García Calderón, Clara Beatriz; García Calderón, Margarita; Peña Gómez, Mª José; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; López-Cornejo, María del Pilar (MDPI, 2020)
Gene therapy is a therapeutic process consisting of the transport of genetic material into cells. The design and preparation ...
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Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletion

Bejarano García, José Antonio; Millán-Uclés, África; Valle Rosado, Iván; Sánchez Abarca, Luis Ignacio; Caballero Velázquez, Teresa; Durán Galván, María José; Pérez Simón, José Antonio; Piraut Palomo, José Ignacio (2016)
It is established that hematopoietic stem cells (HSC) in the hypoxic bone marrow have adapted their metabolism to ...
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Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium

Pontel, Lucas B.; Langenick, Judith; Valle Rosado, Iván; Zhang, Xiao-Yin; Traynor, David; Kay, Robert R.; Patel, Ketan J. (The Company of Biologists, 2016)
As time passes, mutations accumulate in the genomes of all living organisms. These changes promote genetic diversity, but ...
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Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen

Pontel, Lucas B.; Valle Rosado, Iván; Burgos Barragán, Guillermo; Garaycoechea, Juan I.; Yu, Rui; Arends, Mark J.; Patel, Ketan J. (Cell Press, 2015)
Endogenous formaldehyde is produced by numerous biochemical pathways fundamental to life, and it can crosslink both DNA ...
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Final pre-40s maturation depends on the functional integrity of the 60s subunit ribosomal protein l3

García Gómez, Juan José; Fernández Pevida, Antonio; Lebaron, Simon; Valle Rosado, Iván; Tollervey, David W.; Kressler, Dieter; Cruz Díaz, Jesús de la (Public Library of Science, 2014)
Ribosomal protein L3 is an evolutionarily conserved protein that participates in the assembly of early pre-60S particles. ...
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Functional analysis of saccharomyces cerevisiae ribosomal protein Rpl3p in ribosome synthesis

Valle Rosado, Iván; Kressler, Dieter; Cruz Díaz, Jesús de la (Oxford University Press, 2007)
Ribosome synthesis in eukaryotes requires a multitude oftrans-acting factors. These factors act at many steps as the ...
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Npa1p is an essential trans-acting factor required for an early step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae

Valle Rosado, Iván; Cruz Díaz, Jesús de la (Cold Spring Harbor Laboratory Press, 2004)
Ribosome biogenesis requires > 100 nonribosomal proteins, which are associated with different preribosomal particles. The ...