NameGiner García, Mercedes
DepartmentCitología e Histología Normal y Patológica
Knowledge areaBiología Celular
Professional categoryProfesora Titular de Universidad
E-mailRequest
         
  • No. publications

    28

  • No. visits

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Osteoblastic cell behavior and gene expression related to bone metabolism on different titanium surfaces

Velasco-Ortega, Eugenio; Fos-Parra, Isabel; Cabanillas Balsera, Daniel; Gil, Javier; Ortiz García, Iván; Giner García, Mercedes; Bocio-Núñez, Jesús; Montoya García, María José; Jiménez Guerra, Álvaro (MDPI, 2023)
The surface topography of titanium dental implants has a great influence on osseointegration. In this work, we try to ...
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Approach to the Fatigue and Cellular Behavior of Superficially Modified Porous Titanium Dental Implants

Trueba Muñoz, Paloma; Navarro Pintado, Carlos; Rodríguez-Ortiz, José Antonio; Giner García, Mercedes; Montoya García, María José; Delgado-Pujol, Ernesto J.; Rodríguez-Albelo, Luisa Marleny; Torres Hernández, Yadir (MDPI, 2022)
In this work, the fatigue and cellular performance of novel superficially treated porous titanium dental implants made up ...
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Influence of Femtosecond Laser Modification on Biomechanical and Biofunctional Behavior of Porous Titanium Substrates

Beltrán, Ana M.; Giner García, Mercedes; Rodríguez Carballo, Ángel; Trueba Muñoz, Paloma; Rodríguez-Albelo, Luisa Marleny; Vázquez Gámez, María de los Ángeles; Fortio Godinho, Vanda Cristina; Alcudia Cruz, Ana; Amado Paz, José Manuel; López Santos, Carmen (MDPI, 2022)
Bone resorption and inadequate osseointegration are considered the main problems of titanium implants. In this investigation, ...
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Spanish National Registry of Major Osteoporotic Fractures (REFRA) seen at Fracture Liaison Services (FLS): objectives and quality standards

Montoya García, María José; Carbonell Abella, Cristina; Cancio Trujillo, José Manuel; Moro Álvarez, María Jesús; Izquierdo Avino, Rafael; Nogues, Xavier; Giner García, Mercedes (SPRINGER, 2022)
Summary REFRA-FLS is a new registry in Spain aimed at identifying individuals over 50 years of age with a fragility ...
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Electrical Impedance of Surface Modified Porous Titanium Implants with Femtosecond Laser

Navarro González, Paula; Olmo Fernández, Alberto; Giner García, Mercedes; Rodríguez-Albelo, Luisa Marleny; Rodríguez Gómez, Ángel; Torres Hernández, Yadir (MDPI, 2022)
The chemical composition and surface topography of titanium implants are essential to improve implant osseointegration. ...
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DC electrical stimulation enhances proliferation and differentiation on N2a and MC3T3 cell lines

Martín Fernández, Daniel; Bocio-Núñez, Jesús; Fernández Scagliusi, Santiago Joaquín; Pérez García, Pablo; Huertas Sánchez, Gloria; Yúfera García, Alberto; Giner García, Mercedes; Daza Navarro, María Paula (Springer Nature, 2022)
Background: Electrical stimulation is a novel tool to promote the differentiation and proliferation of precursor cells. ...
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Circulating Osteogenic Progenitor Cells Enhanced with Teriparatide or Denosumab Treatment

Giner García, Mercedes; Vázquez Gámez, María de los Ángeles; Miranda, María José; Bocio-Núñez, Jesús; Olmo-Montes, Francisco Jesús; Rico Corral, Miguel Ángel; Colmenero, Miguel Ángel; Montoya García, María José (MDPI, 2022)
Circulating osteogenic precursor (COP) cells are peripheral blood cells with a capacity for osteogenesis. The objective ...
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The Fracture Liaison Service of the Virgen Macarena University Hospital Reduces the Gap in the Management of Osteoporosis, Particularly in Men. It Meets the International Osteoporosis Foundation Quality Standards

Olmo Montes, Francisco Jesús; Hernández Cruz, Blanca; Miranda García, María José; Jiménez Moreno, María Dolores; Vázquez Gámez, María de los Ángeles; Giner García, Mercedes; Colmenero, Miguel Ángel; Pérez Venegas, José J.; Montoya García, María José (MDPI, 2021)
Objectives: To describe the Fracture Liaison Service (FLS), to know the characteristics of the patients attended with ...
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Tribo-mechanical and cellular behavior of superficially modified porous titanium samples using femtosecond laser

Trueba Muñoz, Paloma; Giner García, Mercedes; Rodríguez Carballo, Angel; Beltrán, Ana M.; Amado Paz, José Manuel; Montoya García, María José; Rodríguez-Albelo, Luisa Marleny; Torres Hernández, Yadir (Elsevier, 2021)
In this work, the surface of porous titanium samples obtained by the space-holder technique was treated with a femtosecond ...
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Microstructural and strength changes in trabecular bone in elderly patients with type 2 diabetes mellitus

Giner García, Mercedes; Miranda Díaz, Cristina; Vázquez Gámez, María de los Ángeles; Altea-Manzano, Patricia; Miranda, M.J.; Casado-Díaz, Antonio; Pérez Cano, Ramón; Montoya García, María José (MPDI, 2021)
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide and it is associated with an increased ...
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Fragility fractures and imminent fracture risk in the spanish population: a retrospective observational cohort study

Montoya García, María José; Giner García, Mercedes; Marcos, Rodrigo; García Romero, David; Olmo Montes, Francisco Jesús; Miranda, Mª José; Hernández-Cruz, Blanca; Colmenero, Miguel Ángel; Vázquez Gámez, María de los Ángeles (MDPI, 2021)
Fragility fractures constitute a major public health problem worldwide, causing important high morbidity and mortality ...
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Biocompatibility and Cellular Behavior of TiNbTa Alloy with Adapted Rigidity for the Replacement of Bone Tissue

Giner García, Mercedes; Chicardi Augusto, Ernesto; Costa Martins, Alzenira de Fátima; Santana, Laura; Vázquez Gámez, María de los Ángeles; García Garrido, Cristina; Colmenero, Miguel Ángel; Olmo-Montes, Francisco Jesús; Torres Hernández, Yadir; Montoya García, María José (MDPI, 2021)
In this work, the mechanical and bio-functional behavior of a TiNbTa alloy is evaluated as a potential prosthetic biomaterial ...
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Use of Impedance Spectroscopy for the Characterization of In-Vitro Osteoblast Cell Response in Porous Titanium Bone Implants

Giner García, Mercedes; Olmo Fernández, Alberto; Hernández, Miguel; Trueba Muñoz, Paloma; Chicardi Augusto, Ernesto; Civantos, Ana; Vázquez Gámez, María de los Ángeles; Montoya García, María José; Torres Hernández, Yadir (MDPI, 2020)
The use of titanium implants with adequate porosity (content, size and morphology) could solve the stress shielding ...
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Surface Modification of Porous Titanium Discs Using Femtosecond Laser Structuring

Rodríguez Carballo, Ángel; Trueba Muñoz, Paloma; Amado Paz, José Manuel; Tobar Vidal, María José; Giner García, Mercedes; Amigó Borrás, Vicente; Torres Hernández, Yadir (MDPI, 2020)
The failure of titanium implants is associated with two main problems that include the bone resorption and fracture of the ...
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In Vitro Bone Cell Behavior on Porous Titanium Samples: Influence of Porosity by Loose Sintering and Space Holder Techniques

Civantos, Ana; Giner García, Mercedes; Trueba Muñoz, Paloma; Lascano, Sheila; Montoya García, María José; Arévalo Mora, Cristina María; Vázquez Gámez, María de los Ángeles; Allain, Jean Paul; Torres Hernández, Yadir (MDPI, 2020)
A great variety of powder metallurgy techniques can produce biomimetic porous titanium structures with similar mechanical ...
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Incidence, morbidity and mortality of hip fractures over a period of 20 years in a health area of Southern Spain

Rey Rodríguez, Marta María; Vázquez Gámez, María de los Ángeles; Giner García, Mercedes; Garrachón Vallo, Fernando; Fernández López, Luis; Colmenero, Miguel Ángel; Montoya García, María José (BMJ Journals, 2020)
Objective To evaluate the incidence of osteoporotic hip fracture in the Macarena Health Area (Seville). Setting and ...
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Best Practice Framework of Fracture Liaison Services in Spain and their coordination with Primary Care

Naranjo, A.; Ojeda, S.; Giner García, Mercedes; Balcells-Oliver, M.; Canals, L.; Cancio, J. M.; Montoya García, María José; Prieto-Alhambra, D. (2020)
Summary The coordination of Fracture Liaison Services (FLS) with Primary Care (PC) is necessary for the continuity of care ...
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Estudio de biocompatibilidad y osteointegración de nuevos materiales protésicos

Giner García, Mercedes; Santana, L.; Vázquez Gámez, María de los Ángeles; Colmenero, M.; Olmo, F. J.; Chicardi Augusto, Ernesto; Torres Hernández, Yadir; Montoya García, María José (Ibáñez & Plaza, 2020)
Objetivos Los implantes óseos son utilizados cada vez con mayor frecuencia en la práctica clínica y, entre los materiales, ...
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Influencia de la vitamina D sobre la microestructura y propiedades biomecánicas de pacientes con fractura de cadera.

Montoya García, María José; Vázquez Gámez, María de los Ángeles; Pérez Cano, Ramón; Giner García, Mercedes;  (2017)
Valorar niveles séricos de 25-hidroxivitamina D -25(OH)D-, hormonas con influencia sobre el metabolismo óseo (parathormona ...
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Influencia de la obesidad sobre la microarquitectura y las propiedades biomecánicas en pacientes con fractura de cadera

Giner García, Mercedes; Montoya García, María José; Vázquez Gámez, María de los Ángeles; Pérez Cano, Ramón (2016)
La obesidad y la osteoporosis (OP) son dos patologías muy prevalentes en nuestra sociedad actual. El efecto de la obesidad ...
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Influence of high glucose and advanced glycation end-products (ages) levels in human osteoblast-like cells gene expression

Miranda Díaz, Cristina; Giner García, Mercedes; Montoya García, María José; Vázquez Gámez, María de los Ángeles; Miranda García, María José; Pérez Cano, Ramón (2016)
Background: Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporotic fracture. Several factors ...
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¿Qué son los microARNs? Posibles biomarcadores y dianas terapéuticas en la enfermedad osteoporótica

Giner García, Mercedes; Montoya García, María José; Vázquez Gámez, María de los Ángeles; Miranda Díaz, Cristina; Miranda, M.J.; Pérez Cano, Ramón (Sociedad Espanola de Investigacion Osea y del Metabolismo Mineral (SEIOMM), 2016)
Los micro-ARN (miRs) son pequeñas moléculas de ARN no codificantes que regulan la expresión génica a nivel post-transcripcional. ...
PhD Thesis
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Influencia de la diabetes mellitus tipo 1 y su control metabólico sobre la proporción de células de extirpe osteoblástica en sangre periférica, en niños y adultos jóvenes

Pérez Temprano, Ramón; Giner García, Mercedes; Pérez Cano, Ramón (2015)
En la introducción se hace una puesta al día de las complicaciones metabólicas y la afectación de los distintos aparatos ...
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Differences in osteogenic and apoptotic genes between osteoporotic and osteoarthritic patients

Giner García, Mercedes; Vázquez Gámez, María de los Ángeles; Pérez Cano, Ramón; Montoya García, María José; Miranda Díaz, Cristina (2013)
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Estudio génico (OPG, RANKL, Runx2 y receptores AGE) en cultivos de osteoblastos humanos de pacientes con diabetes mellitus tipo 2 y fractura de cadera. Influencia de los niveles de glucosa y AGEs

Miranda Díaz, Cristina; Giner García, Mercedes; Montoya García, María José; Vázquez Gámez, María de los Ángeles; Moruno García, Rosa María; Miranda García, María José; Pérez Cano, Ramón (Sociedad Española de Investigación Ósea y del Metabolismo Mineral, 2012)
Introducción: La diabetes mellitus (DM) tipo 2 se asocia a un mayor riesgo de fractura osteoporótica. Se han señalado ...
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Vertebral fractures in patients with inflammatory bowel disease compared with a healthy population: a prospective case-control study

Pérez Cano, Ramón; Giner García, Mercedes; López, Enrique; Montoya García, María José; Pérez Temprano, Ramón (2012)
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Modifying RANKL/OPG mRNA expression in differentiating and growing human primary osteoblasts

Giner García, Mercedes; Montoya García, María José; Vázquez Gámez, María de los Ángeles; Ríos Moreno, María José; Moruno García, Rosa María; Miranda García, María José; Pérez Cano, Ramón (Georg Thieme, 2008)
The OPG / RANKL system in primary cultures of human osteoblasts has been studied by di ff erent authors. However, very ...
PhD Thesis
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Aislamiento, purificación y caracterización de los alérgenos presentes en la semilla de lupinus albus (altramuz)

Giner García, Mercedes; Conde Hernández, José; Martínez Garate, Alberto; Monteseirín Mateo, Francisco Javier (2002)
El problema principal que nos encontramos al estudiar la alergia alimentaria al Lupinus albus, es que los alérgenos mayores ...