Sol-gel deposition of hydroxyapatite coatings on porous titanium for biomedical applications

Abstract

The stress shielding and the poor osseointegration in titanium implants are still problems to be resolved. In this context, this work proposes a balanced solution. Titanium samples were fabricated, with a porosity of 100-200 µm of pore size employing space-holder technique (50 vol. % NH4HCO3, 800 MPa at 1250 ºC during 2h under high vacuum conditions), obtaining a good equilibrium between stiffness and mechanical resistance. The porous titanium substrates were coated with hydroxyapatite, obtained by sol-gel technique: immersion, dried at 80ºC and heat treatment at 450ºC during 5h under vacuum conditions. Phases, surface morphology and interfacial microstructure of the transverse section were analyzed by Micro-Computed Tomography, SEM and confocal laser, as well as the infiltration capability of the coating into the metallic substrate pores. The FTIR and XRD showed the crystallinity of the phases and the chemical composition homogeneity of the coating. The size and interconnected pores obtained allow the infiltration of hydroxyapatite (HA), possible bone ingrowth and osseointegration. The scratch resistance of the coating corroborated a good adherence to the porous metallic substrate. The coated titanium samples have a biomechanical and biofunctional equilibrium, as well as a potential use in biomedical applications (partial substitution of bone tissue).