dc.creator | Blumer, Roland | es |
dc.creator | Streicher, Johannes | es |
dc.creator | Davis López de Carrizosa, María América | es |
dc.creator | Rodríguez de la Cruz, Rosa María | es |
dc.creator | Pastor Loro, Ángel Manuel | es |
dc.date.accessioned | 2018-02-23T17:20:34Z | |
dc.date.available | 2018-02-23T17:20:34Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Blumer, R., Streicher, J., Davis López de Carrizosa, M.A., Rodríguez de la Cruz, R.M. y Pastor Loro, Á.M. (2017). Palisade endings of extraocular muscles develop postnatally following different time courses. Investigative Ophthalmology and Visual Science, 58 (12), 1-17. | |
dc.identifier.issn | 0146-0404 (impreso) | es |
dc.identifier.issn | 1552-5783 (electrónico) | es |
dc.identifier.uri | https://hdl.handle.net/11441/70573 | |
dc.description.abstract | PURPOSE. To analyze in a frontal-eyed mammal (cat) the postnatal development of palisade
endings in extraocular muscles (EOMs) and to compare the spatiotemporal and quantitative
patterns of palisade endings among individual rectus muscles.
METHODS. Cats of different ages ranging from birth to adult stage were studied. EOM wholemount
preparations were fluorescently labeled using six combinations of triple staining and
analyzed in the confocal laser scanning microscope.
RESULTS. Palisade endings developed postnatally and passed in each rectus muscle through the
same, three developmental steps but in a heterochronic sequence and to a different final
density per muscle. Specifically, palisade ending development was first completed in the
medial rectus and later in the inferior, lateral, and superior rectus. The highest density of
palisade endings was observed in the medial rectus and the lowest in the lateral rectus
whereas values for the inferior and superior rectus were in between. Palisade endings
expressed high levels of growth associated protein 43 during development and were supplied
by axons that established motor terminals.
CONCLUSIONS. Cats open their eyes 7 to 10 days after birth and later develop a complex threedimensional
visuomotor climbing and jumping behavior depending on accurate binocular
vision and fine tuning of the ocular movements. Our findings indicate that palisade ending
development correlates with important landmarks in visuomotor behavior and provide
support for our previous notion that palisade endings play an important role for convergence
eye movements in frontal-eyed species. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Association for Research in Vision and Ophthalmology | es |
dc.relation.ispartof | Investigative Ophthalmology and Visual Science, 58 (12), 1-17. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Oculomotor | es |
dc.subject | GAP43 | es |
dc.subject | Multiply-innervated muscle fibers | es |
dc.subject | Singly-innervated muscle fibers | es |
dc.subject | Convergence | es |
dc.subject | Frontal-eyed animals | es |
dc.subject | Extraocular muscles | es |
dc.subject | Eye movements | es |
dc.title | Palisade endings of extraocular muscles develop postnatally following different time courses | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Fisiología | es |
dc.relation.publisherversion | http://dx.doi.org/10.1167/ iovs.17-22643 | es |
dc.identifier.doi | 10.1167/ iovs.17-22643 | es |
idus.format.extent | 17 p. | es |
dc.journaltitle | Investigative Ophthalmology and Visual Science | es |
dc.publication.volumen | 58 | es |
dc.publication.issue | 12 | es |
dc.publication.initialPage | 1 | es |
dc.publication.endPage | 17 | es |