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The binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain

 

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Opened Access The binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain
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Author: Aroca Aguilar, Ángeles
Cruz Gallardo, Isabel
Díaz Moreno, Irene
Angulo Álvarez, Jesús
Gunzburg, Menachen J.
Sivakumaran, Andrew
Yoon, Je-Hyun
Department: Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular
Date: 2014
Published in: RNA Biology, 11 (6), 766-776.
Document type: Article
Abstract: T-cell intracellular antigen-1 (TIA-1) is a key DNA/RNA binding protein that regulates translation by sequestering target mRNAs in stress granules (SG) in response to stress conditions. TIA-1 possesses three RNA recognition motifs (RRM) along with a...
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Cite: Aroca Aguilar, Á., Cruz Gallardo, I., Díaz Moreno, I., Angulo Álvarez, J., Gunzburg, M.J., Sivakumaran, A. y Yoon, J. (2014). The binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain. RNA Biology, 11 (6), 766-776.
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URI: https://hdl.handle.net/11441/70120

DOI: http://dx.doi.org/10.4161/rna.28801

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