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Zinc eluted from siliconized latex urinary catheters decreases OprD expression, causing carbapenem resistance in Pseudomonas aeruginosa

dc.creatorConejo Gonzalo, Mª Carmenes
dc.creatorGarcía Luque, Isabeles
dc.creatorMartínez Martínez, Luises
dc.creatorPicabea de la Peña, Leandroes
dc.creatorPascual Hernández, Álvaroes
dc.date.accessioned2017-07-27T11:45:30Z
dc.date.available2017-07-27T11:45:30Z
dc.date.issued2003-07-01
dc.identifier.citationConejo Gonzalo, M.C., García Luque, I., Martínez Martínez, L., Picabea de la Peña, L. y Pascual Hernández, Á. (2003). Zinc eluted from siliconized latex urinary catheters decreases OprD expression, causing carbapenem resistance in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy, 47 (7), 2313-2315.
dc.identifier.issn0066-4804 (impreso)es
dc.identifier.issn1098-6596 (electrónico)es
dc.identifier.urihttp://hdl.handle.net/11441/63346
dc.description.abstractThe activities of carbapenems against Pseudomonas aeruginosa decreased in the presence of siliconized latex urinary catheters (SLUCs). This effect was associated with the loss of OprD. The zinc that eluted from SLUCs is responsible for this phenomenon. We have found that zinc exerts a negative effect on the expression of OprD, the porin responsible for carbapenem entry into P. aeruginosa.es
dc.description.sponsorshipDirección General de Investigación del Ministerio de Ciencia y Tecnología SAF2000-035es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherAmerican Society for Microbiologyes
dc.relation.ispartofAntimicrobial Agents and Chemotherapy, 47 (7), 2313-2315.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleZinc eluted from siliconized latex urinary catheters decreases OprD expression, causing carbapenem resistance in Pseudomonas aeruginosaes
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Microbiologíaes
dc.relation.projectIDSAF2000-035es
dc.relation.publisherversionhttp://dx.doi.org/10.1128/AAC.47.7.2313-2315.2003es
dc.identifier.doi10.1128/AAC.47.7.2313-2315.2003es
idus.format.extent3 p.es
dc.journaltitleAntimicrobial Agents and Chemotherapyes
dc.publication.volumen47es
dc.publication.issue7es
dc.publication.initialPage2313es
dc.publication.endPage2315es
dc.contributor.funderMinisterio de Ciencia y Tecnología (MCYT). España

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