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Influence of cow or goat milk consumption on antioxidant defence and lipid peroxidation during chronic iron repletion

Opened Access Influence of cow or goat milk consumption on antioxidant defence and lipid peroxidation during chronic iron repletion

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Autor: Díaz Castro, Javier
Pérez Sánchez, Luis Javier
Ramírez López-Frías, Mercedes
López Aliaga, Inmaculada
Nestares, Teresa
Muñoz Alférez, María José
Ojeda Murillo, María Luisa
Departamento: Universidad de Sevilla. Departamento de Fisiología
Fecha: 2012
Publicado en: British Journal of Nutrition, 108 (1), 1-8.
Tipo de documento: Artículo
Resumen: Despite Fe deficiency and overload having been widely studied, no studies are available about the influence of milk consumption on antioxidant defence and lipid peroxidation during the course of these highly prevalent cases. The objective of the present study was to assess the influence of cow or goat milk-based diets, either with normal or Fe-overload, on antioxidant defence and lipid peroxidation in the liver, brain and erythrocytes of control and anaemic rats after chronic Fe repletion. Weanling male rats were randomly divided into two groups: a control group receiving a normal-Fe diet (45 mg/kg) and an anaemic group receiving a low-Fe diet (5 mg/kg) for 40 d. Control and anaemic rats were fed goat or cow milk-based diets, either with normal Fe or Fe-overload (450 mg/kg), for 30 or 50 d. Fe-deficiency anaemia did not have any effect on antioxidant enzymes or lipid peroxidation in the organs studied. During chronic Fe repletion, superoxide dismutase (SOD) activity was higher ...
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Cita: Díaz Castro, J., Pérez Sánchez, L.J., Ramírez López-Frías, M., López Aliaga, I., Nestares, T., Muñoz Alférez, M.J. y Ojeda Murillo, M.L. (2012). Influence of cow or goat milk consumption on antioxidant defence and lipid peroxidation during chronic iron repletion. British Journal of Nutrition, 108 (1), 1-8.
Tamaño: 164.9Kb
Formato: PDF

URI: http://hdl.handle.net/11441/45388

DOI: 10.1017/S0007114511005204

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