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Efectos de la ranitidina sobre células parietales en regeneración : Estudio estereológico

 

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Opened Access Efectos de la ranitidina sobre células parietales en regeneración : Estudio estereológico
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Author: Torreblanca López, José
Ibáñez Delgado, Francisco
López Campos, José Luis
Moreno Onorato, Francisco Javier
Department: Universidad de Sevilla. Departamento de Biología Celular
Date: 1990
Published in: Revista española de las enfermedades del aparato digestivo,78(6), 335-340
Document type: Article
Abstract: In this work, we have carried out a stereological and morphological study in order to verify the effects of Ranitidine on regenerating parietal cells. We have used a control group and operated or non-operated groups treated with 2, 10 and 50 mg/kglday Ranitidine. In operated groups an ulcer was provoked by cauterization with a metallic plate in the gastric fundus. Groups treated with high doses of Ranitidine showed an increase in the connective tissue of the gastrlc mucosa. The stereological study in treated groups shows a decrease in the parietal voiume density, and an increase in the cellular profile. Changes detected in the parietal volume density would originate a decrease in the production of CIH Para comprobar la acción de la ranitidina sobre células parietales en regeneración hemos realizado un estudio morfológico y estereológico. Para ello utilizamos grupos controles y de tratamiento con el fármaco a dosis de dos, 10 y 50 mg!kg/día, o...
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URI: http://hdl.handle.net/11441/40657

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