Listar Instituto de Biomedicina de Sevilla (IBIS) por título
Mostrando ítems 169-188 de 200
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Sex differences in motor and non-motor symptoms among Spanish patients with Parkinson’s disease
(MDPI, 2023)Background and objective: Sex plays a role in Parkinson’s disease (PD) mechanisms. We analyzed sex difference manifestations ...
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Single nucleotide polymorphisms as prognostic and predictive biomarkers in renal cell carcinoma.
(Impact Journals, 2017)Despite major advances in the knowledge of the molecular basis of renal cell carcinoma, prognosis is still defined using ...
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Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan- Neuronal Activation in the Female Mouse.
(2016-10-14)Gender difference in Parkinson’s disease (PD) suggests that female sex steroids may promote dopaminergic neuron survival ...
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Study protocol for a randomized clinical trial to assess 7 versus 14-days of treatment for Pseudomonas aeruginosa bloodstream infections (SHORTEN-2 trial)
(2022-12-22)Background Research priorities in Antimicrobial Stewardship (AMS) have rapidly evolved in the last decade. The need for ...
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Substantia nigra dopaminergic neurons and striatalinterneurons are engaged in three parallel but interdependentpostnatal neurotrophic circuits
(Anatomical Society of Great Britain and Ireland, 2018-06-11)The striatum integrates motor behavior using a well‐defined microcircuit whose individual components are independently ...
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Surgical management of complex perianal fistula revisited in a systematic review: a critical view of available scientific evidence
(2023)Background Treating complex perianal fstulas in Crohn’s disease patients remains a challenge. Classical surgical treatments ...
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Survival Outcomes and Health-Related Quality of Life in Older Adults Diagnosed with Acute Myeloid Leukemia Receiving Frontline Therapy in Daily Practice
(MPDI, 2023-11-28)Acute myeloid leukemia has a poor prognosis in older adults, and its management is often unclear due to its underrepresentation ...
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Targeted Simplification Versus Antipseudomonal Broad-Spectrum Beta-Lactams in Patients With Bloodstream Infections Due to Enterobacteriaceae (SIMPLIFY): A Study Protocol for a Multicentre, Open-Label, Phase III Randomised, Controlled, Non-Inferiority Clinical Trial.
(2017-06-09)Introduction Within the context of antimicrobial stewardship programmes, de-escalation of antimicrobial therapy is one ...
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Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound
(Public Library of Science, 2012-05-18)Aquaporins (AQPs) are membrane channels that conduct water and small solutes such as glycerol and are involved in many ...
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TARTESSUS: a customized electrospun drug delivery system loaded with irinotecan for local and sustained chemotherapy release in pancreatic cancer
(MDPI, 2023)Post-surgical chemotherapy in pancreatic cancer has notorious side effects due to the high dose required. Multiple devices ...
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Testing for alpha-1 antitrypsin in COPD in outpatient respiratory clinics in Spain: A multilevel, cross-sectional analysis of the EPOCONSUL study
(Public Library of Science, 2018-06-28)Background Alpha-1 antitrypsin deficiency (AATD) is the most common hereditary disorder in adults, but is under-recognized. ...
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The carotid body, a neurogenic niche in the adult peripheral nervous system
(Univ pisa, 2010)We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ in the ...
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The carotid body: a physiologically relevant germinal niche in the adult peripheral nervous system
(Springer, 2018-11-29)Oxygen constitutes a vital element for the survival of every single cell in multicellular aerobic organisms like mammals. ...
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The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye
(Company of Biologists Limited, 2015-01)Embryopathies that develop as a consequence of maternal diabetes have been studied intensely in both experimental and ...
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The essential role of IL-17 as the pathogenetic link between psoriasis and metabolic-associated fatty liver disease
(MDPI, 2023)Interleukin 17 (IL-17) is an effector cytokine that plays a key role in the pathogenesis of both psoriasis and ...
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The impact of initial antibiotic treatment failure: Real-world insights in patients with complicated, health care-associated intra-abdominal infection
(Dove, 2019-01-31)Purpose: The RECOMMEND study (NCT02364284; D4280R00005) assessed the clinical management patterns and treatment outcomes ...
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The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation
(Ferrata Storti Foundation, 2012)Background We have previously shown that bortezomib induces a depletion of alloreactive T cells and allows the expansion ...
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The prognosis of patients hospitalized with a first episode of heart failure, validation of two scores: PREDICE and AHEAD
(2019-02-21)Purpose: Heart failure (HF) is a chronic, frequent and disabling condition but with a modifiable course and a large ...