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- Listar Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) por autor
Listar Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) por autor "Luna Varo, Rosa María"
Mostrando ítems 1-7 de 7
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Artículo
DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
Marchena Cruz, Esther; Camino, Lola P.; Bhandari, Jay; Pinela Da Silva, Sonia Cristina; Marqueta Gracia, José Javier; Amdeen, Shahad A.; Guillén Mendoza, Cristina; García Rubio, María Luisa; Calderón Montaño, José Manuel; Xue, Xiaoyu; Luna Varo, Rosa María; Aguilera López, Andrés (Elsevier, 2023)Unscheduled R loops can be a source of genome instability, a hallmark of cancer cells. Although targeted proteomic ...
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Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability
Salas Armenteros, Irene; Barroso Ceballos, Sonia Inés; García Rondón, Ana; Pérez Calero, Mónica; Andújar, Eloísa; Luna Varo, Rosa María; Aguilera López, Andrés (Elsevier, 2019)THO/TREX is a conserved complex with a role in messenger ribonucleoprotein biogenesis that links gene expression and genome ...
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Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers
Luna Varo, Rosa María; Japón Rodríguez, Miguel Ángel; Sáez, Carmen; Domínguez Sánchez, María Salud; Aguilera López, Andrés (2011)One key step in gene expression is the biogenesis of mRNA ribonucleoparticle complexes (mRNPs). Formation of the mRNP ...
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Artículo
Expression of human RECQL5 in Saccharomyces cerevisiae causes transcription defects and transcription-associated genome instability
Lafuente Barquero, Juan Francisco; Svejstrup, Jesper Q.; Luna Varo, Rosa María; Aguilera López, Andrés (Springer Nature, 2024-05-26)RECQL5 is a member of the conserved RecQ family of DNA helicases involved in the maintenance of genome stability that is ...
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Human THO–Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability
Salas Armenteros, Irene; Pérez Calero, Carmen; Bayona Feliu, Aleix; Tumini, Emanuela; Luna Varo, Rosa María; Aguilera López, Andrés (Wiley-Blackwell, 2017)R-loops, formed by co-transcriptional DNA–RNA hybrids and a displaced DNA single strand (ssDNA), fulfill certain positive ...
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Artículo
The THO Complex as a Paradigm for the Prevention of Cotranscriptional R-Loops
Luna Varo, Rosa María; García Rondón, Ana; Pérez Calero, Carmen; Salas Armenteros, Irene; Aguilera López, Andrés (Cold Spring Harbor Laboratory Press, 2019)Different proteins associate with the nascent RNA and the RNA polymerase (RNAP) to catalyze the transcription cycle and ...
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Artículo
Transcription at the proximity of the nuclear pore: A role for the THP1-SAC3-SUS1-CDC31 (THSC) complex
Luna Varo, Rosa María; González Aguilera, Cristina; Aguilera López, Andrés (Landes Bioscience, 2009)A key aspect of eukaryotic gene expression is the coupling of transcription with RNA processing, polyadenylation and export. ...