• Artículo
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      Gene gating at nuclear pores prevents the formation of R loops 

      Gaillard, Hélène; García Benítez, Francisco; Aguilera López, Andrés (Taylor and Francis Ltd., 2018)
      Transcription is an important source of genetic variability. A large amount of transcription-associated genome variation ...
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      Manganese is a physiologically relevant TORC1 activator in yeast and mammals 

      Nicastro, Raffaele; Gaillard, Hélène; Zarzuela, Laura; Peli-Gulli, Marie-Pierre; Fernández García, Elisabet; Tomé, Mercedes; García Rodríguez, Néstor; Durán, Raúl V.; De Virgilio, Claudio; Wellinger, Ralf Erik (eLife Sciences Publications, 2022)
      The essential biometal manganese (Mn) serves as a cofactor for several enzymes that are crucial for the prevention of human ...
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      The Nup84 complex coordinates the DNA damage response to warrant genome integrity 

      Gaillard, Hélène; Santos Pereira, José María; Aguilera López, Andrés (Oxford University Press, 2019)
      DNA lesions interfere with cellular processes such as transcription and replication and need to be adequately resolved to ...
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      Transcription as a Threat to Genome Integrity 

      Gaillard, Hélène; Aguilera López, Andrés (Annual Reviews Inc., 2016)
      Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and genome rearrangements, ...