idUS - Author profile: Gaillard, Hélène

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Name	Gaillard, Hélène
Department	Genética
Knowledge area	Genética
Professional category	Profesora Titular de Universidad
E-mail	Request

No. publications

13
No. visits

1956
No. downloads

2013

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Publications
PhD Thesis Role of FACT and other chromatin-related factors in the origin of genetic instability Soler Oliva, María Eugenia; Aguilera López, Andrés; Gaillard, Hélène (2024) El mantenimiento de la integridad del genoma es un requisito indispensable para garantizar el correcto funcionamiento de ...
Article Manganese Stress Tolerance Depends on Yap1 and Stress-Activated MAP Kinases García de Oya, Inés; Jiménez Gutiérrez, Elena; Gaillard, Hélène; Molina, María; Martín, Humberto; Wellinger, Ralf Erik (Multidisciplinary Digital Publishing Institute (MDPI), 2022) Understanding which intracellular signaling pathways are activated by manganese stress is crucial to decipher how metal ...
Article Manganese is a physiologically relevant TORC1 activator in yeast and mammals Nicastro, Raffaele; Gaillard, Hélène; Zarzuela, Laura; Peli-Gulli, Marie-Pierre; Fernández García, Elisabet; Tomé, Mercedes; García Rodríguez, Néstor; Durán, Raúl V.; De Virgilio, Claudio; Wellinger, Ralf Erik (eLife Sciences Publications, 2022) The essential biometal manganese (Mn) serves as a cofactor for several enzymes that are crucial for the prevention of human ...
Article The human nucleoporin Tpr protects cells from RNA-mediated replication stress Kosar, Martin; Giannattasio, Michele; Piccini, Daniele; Maya Mendoza, Apolinar; García Benítez, Francisco; Bartkova, Jirina; Barroso Ceballos, Sonia Inés; Gaillard, Hélène; Martini, Emanuele; Restuccia, Umberto; Ramírez Otero, Miguel Ángel; Garre, Massimiliano; Verga, Eleonora; Andújar Sánchez, Miguel; Maynard, Scott; Hodny, Zdenek; Costanzo, Vincenzo; Kumar, Amit; Bachi, Angela; Aguilera López, Andrés; Bartek, Jiri; Foiani, Marco (Springer Nature, 2021) Although human nucleoporin Tpr is frequently deregulated in cancer, its roles are poorly understood. Here we show that Tpr ...
Article The Nup84 complex coordinates the DNA damage response to warrant genome integrity Gaillard, Hélène; Santos Pereira, José María; Aguilera López, Andrés (Oxford University Press, 2019) DNA lesions interfere with cellular processes such as transcription and replication and need to be adequately resolved to ...
PhD Thesis Inestabilidad genética asociada a R-loops. García Benítez, Francisco; Aguilera López, Andrés; Gaillard, Hélène (2018) La inestabilidad genómica es una patología celular, la cual se produce cuando una célula acumula variaciones genéticas que ...
Article Gene gating at nuclear pores prevents the formation of R loops Gaillard, Hélène; García Benítez, Francisco; Aguilera López, Andrés (Taylor and Francis Ltd., 2018) Transcription is an important source of genetic variability. A large amount of transcription-associated genome variation ...
Article Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability García Benítez, Francisco; Gaillard, Hélène; Aguilera López, Andrés (National Academy of Sciences, 2017) During transcription, the mRNA may hybridize with DNA, forming an R loop, which can be physiological or pathological, ...
Article Transcription as a Threat to Genome Integrity Gaillard, Hélène; Aguilera López, Andrés (Annual Reviews Inc., 2016) Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and genome rearrangements, ...
Article Cleavage factor I links transcription termination to DNA damage response and genome integrity maintenance in Saccharomyces cerevisiae Gaillard, Hélène; Aguilera López, Andrés (Public Library of Science, 2014) During transcription, the nascent pre-mRNA undergoes a series of processing steps before being exported to the cytoplasm. ...
Article Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair Gaillard, Hélène; Tous Rivera, Cristina; Botet, Javier; González Aguilera, Cristina; Quintero, María José; Viladevall, Laia; García Rubio, María Luisa; Rodríguez Gil, Alfonso; Marín, Antonio; Ariño, Joaquín; Revuelta, José Luis; Chávez de Diego, Sebastián; Aguilera López, Andrés (Public Library of Science, 2009) RNA polymerases frequently deal with a number of obstacles during transcription elongation that need to be removed for ...
Article A novel class of Mrna-containing cytoplasmic granules are produced in response to UV-irradiation Gaillard, Hélène; Aguilera López, Andrés (American Society for Cell Biology, 2008) Nucleic acids are substrates for different types of damage, but little is known about the fate of damaged RNAs. We addressed ...
Article A new connection of mRNP biogenesis and export with transcription-coupled repair Gaillard, Hélène; Wellinger, Ralf Erik; Aguilera López, Andrés (Oxford University Press, 2007) Although DNA repair is faster in the transcribed strand of active genes, little is known about the possible contribution ...