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Mostrando ítems 11-20 de 108
Artículo
Impact of COVID-19 on liver disease: From the experimental to the clinic perspective.
(Baishideng Publishing Group Inc, 2021)
Coronavirus disease 2019 (COVID-19) has caused a global pandemic unprecedented in over a century. Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a predominantly respiratory infection, various ...
Artículo
Real-world evidence on non-invasive tests and associated cut-offs used to assess fibrosis in routine clinical practice
(Elsevier, 2022)
Background & Aims Non-invasive tests (NITs) offer a practical solution for advanced fibrosis identification in non-alcoholic fatty liver disease (NAFLD). Despite increasing implementation, their use is not standardised, ...
Artículo
Mistranslation drives alterations in protein levels and the effects of a synonymous variant at the fibroblast growth factor 21 locus
(WILEY, 2021)
Fibroblast growth factor 21 (FGF21) is a liver-derived hormone with pleiotropic beneficial effects on metabolism. Paradoxically, FGF21 levels are elevated in metabolic diseases. Interventions that restore metabolic ...
Artículo
Disease severity predicts higher healthcare costs among hospitalized nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH) patients in Spain
(Lippincott, Williams & Wilkins, 2020)
The rising prevalence of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) presents many public health challenges, including a substantial impact on healthcare resource utilization and costs. ...
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Artículo
Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis: A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects
(2021-04)
Background and Aim: Histological score systems may not fully capture the essential nonalcoholic steatohepatitis (NASH) features, which is one of the leading causes of screening failure in clinical trials. We assessed the ...
Artículo
Artículo
The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology
(Elsevier, 2020)
Herein, we describe, for the first time, 3 different clinical courses of acute decompensation (AD) of cirrhosis after hospital admission. The first clinical course includes patients who develop acute-on-chronic liver failure ...
Artículo
Emerging pharmacological treatment options for MAFLD
(2022)
Metabolic dysfunction–associated fatty liver disease (MAFLD) prevalence and incidence is rising globally. It is associated with metabolic comorbidities, obesity, overweight, type 2 diabetes mellitus, and at least two ...
Artículo
Clinical application of Magnetic resonance elastography in hepatocellular carcinoma: From diagnosis to prognosis
(Elsevier, 2023)
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a major public health problem worldwide. Liver fibrosis is closely correlated with liver functional reserve and the risk of HCC development. Meanwhile, ...