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Mostrando ítems 1-10 de 14
Artículo
Properties of Calcium and Potassium Currents of Clonal Adrenocortical Cells
(1989)
The ionic currents of clonal Y-1 adrenocortical cells were studied using the whole-cell variant of the patch-clamp technique. These cells had two major current components: a large outward current carried by K ions, and a ...
Artículo
Hypoxia induces voltage-dependent Ca2+ entry and quantal dopamine secretion in carotid body glomus cells
(1994)
We have investigated the changes of cytosolic [Ca2+1 and the secretory -activity in single glomus cells dispersed from rabbit carotid bodies during exposure to solutions with variable 02 tension (Po2). In normoxic conditions ...
Artículo
Oxygen sensing by ion channels and chemotransduction in single glomus cells
(1996)
We have monitored cytosolic [Ca2+] and dopamine release in intact fura-2-loaded glomus cells with microfluoroimetry and a polarized carbon fiber electrode. Exposure to low PO2 produced a rise of cytosolic [Ca2+] with two ...
Tesis Doctoral
Acoplamiento excitación-contracción en músculo liso: nuevo papel metabotrópico de los canales de calcio en la regulación del tono vascular
(2006-01-17)
El músculo liso es un tejido que se encuentra generalmente recubriendo órganos (músculo liso visceral: tubo digestivo, colon, próstata, etc.) y vasos sanguíneos (músculo liso vascular: venas y arterias), aunque también ...
Artículo
Ionic currents in dispersed chemoreceptor cells of the mammalian carotid body
(1989)
Ionic currents of enzymatically dispersed type I and type II cells of the carotid body have been studied using the whole cell variant of the patch-clamp technique. Type II cells only have a tiny, slowly activating outward ...
Patente. Invención
Utilización en composiciones farmacológicas de agentes con efecto reductor o inductor de hipoxia
(Oficina Española de Patentes y Marcas (OEPM), 1999-07-01)
Utilización en composiciones farmacológicas de agentes con efecto reductor o inductor de hipoxia. Se propone como nueva la utilización en preparados farmacológicos de agentes reductores, y en general aquellos que produzcan ...
Patente
Composiciones y preparaciones combinadas para el tratamiento del vasoespasmo arterial
(Oficina Española de Patentes y Marcas , 2015-04-27)
Composición farmacéutica y preparación combinada que comprende un inhibidor de la proteína quinasa C junto a un inhibidor de Rho quinasa, y/o un inhibidor de los canales de Ca2+ tipo L voltaje dependientes, para su uso en ...
Artículo
Oxygen-sensitive calcium channels in vascular smooth muscle and their possible role in hypoxic arterial relaxation
(1995)
We have investigated the modifications of cytosolic [Ca2+] and the activity of Ca2+ channels in freshly dispersed arterial myocytes to test whether lowering 02 tension (P02) directly influences Ca2+ homeostasis in these ...
Tesis Doctoral
Artículo
Metabotropic Ca2+ channel-induced Ca2+ release and ATP-dependent facilitation of arterial myocyte contraction
(2006)
Voltage-gated Ca2_ channels in arterial myocytes can mediate Ca2_ release from the sarcoplasmic reticulum and, thus, induce contraction without the need of extracellular Ca2_ influx. This metabotropic action of Ca2_ channels ...