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Mostrando ítems 11-20 de 44
Artículo
Vitamin C and the Red Wine Polyphenol Resveratrol - but not Curcumin and the Glycolysis Inhibitors 2- Deoxyglucose, Dichloroacetate and 3-Bromopyruvate - Induce Selective Cytotoxicity against Lung Cancer Cells.
(Biomedical Publisher, 2013)
Cancer statistics show that the most commonly diagnosed cancer in the world is lung cancer, that over 50% of patients diagnosed with this cancer have distant metastasis, and that only 4% of these patients manage to survive ...
Artículo
Cytotoxic activity of methanolic extract and two alkaloids extracted from seeds of Peganum harmala L.
(Natural Remedies Pvt Ltd, 2005)
To study the cytotoxic activity of P. harmala. Materials and method: The alkaloids harmine and harmaline have been isolated from a methanolic extract from the seeds of P. harmala L. and have been characterized by ...
Artículo
Screening for selective anticancer activity of plants from Grazalema Natural Park, Spain
(Taylor & Francis, 2019-12-02)
Since plants are an important source of anticancer drugs, we have carried out a random screening for selective anticancer activity of 57 extracts from 45 plants collected in Grazalema Natural Park, an area in the South of ...
Artículo
Dichloroacetate, 2-Deoxyglucose and a Hydroalcoholic Extract from the Skin of the Fruit of Solanum melongena (Aubergine) Induce Selective Anticancer Activity against Melanoma Cells
(Biomedical Publisher, 2013)
Prognosis of melanoma patients with metastatic disease is very poor. For example, over 95% of melanoma patients with three or more sites of metastatic disease die within 1 year. Treatment failure usually occurs because the ...
Artículo
Digoxin, HIF-1, and cancer
(National Academy of Sciences, 2009)
Artículo
Selective amino acid restriction therapy (SAART): a non-pharmacological strategy against all types of cancer cells
(2015)
Metastasis will continue to be an incurable disease for most patients until we develop highly selective anticancer therapies. The development of these therapies requires finding and exploiting major differences between ...
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Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside
(Wiley, 2018)
Several clinically useful anticancer drugs selectively kill cancer cells by inducing DNA damage; the genomic instability and DNA repair defects of cancer cells make them more vulnerable than normal cells to the cytotoxicity ...
Artículo
The Cardiac Glycosides Digitoxin, Digoxin and Ouabain Induce a Potent Inhibition of Glycolysis in Lung Cancer Cells
(Biomedical Publisher, 2013)
Cardiac glycosides are promising anticancer drugs. We have recently shown that the cardiac glycosides digitoxin, digoxin and ouabain induce selective killing of lung cancer cells, and that the cytotoxicity of digitoxin ...
Artículo
Artificial Diets with Altered Levels of Sulfur Amino Acids Induce Anticancer Activity in Mice with Metastatic Colon Cancer, Ovarian Cancer and Renal Cell Carcinoma
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Sulfur-containing amino acids methionine (Met), cysteine (Cys) and taurine (Tau) are common dietary constituents with important cellular roles. Met restriction is already known to exert in vivo anticancer activity. ...