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Mostrando ítems 41-44 de 44
Artículo
5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair
(Oxford University Press, 2013)
5-Aza-2'-deoxycytidine (5-azadC) is a DNA methyltransferase (DNMT) inhibitor increasingly used in treatments of hematological diseases and works by being incorporated into DNA and trapping DNMT. It is unclear what DNA ...
Artículo
Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
(MDPI AG, 2016)
Epidemiological studies have found a positive association between coffee consumption and a lower risk of cardiovascular disorders, some cancers, diabetes, Parkinson and Alzheimer disease. Coffee consumption, however, has ...
Artículo
Consumption of the Dietary Flavonoids Quercetin, Luteolin and Kaempferol and Overall Risk of Cancer - A Review and Meta-Analysis of the Epidemiological Data
(Biomedical Publisher, 2013)
Numerous epidemiological and preclinical studies suggest that flavonoids may play an important role in the decreased risk of cancer associated with a diet rich in plant-derived foods. In this article, we have reviewed the ...
Artículo
Effect of DNA repair deficiencies on the cytotoxicity of resveratrol
(2015)
Numerous preclinical studies have shown that the naturally-occurring polyphenol resveratrol may produce health-beneficial effects in a variety of disorders, including cancer, diabetes, Alzheimer, and cardiovascular ...