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Now showing items 41-50 of 314
Article
Clonal patterns in phaeochromocytomas and MEN-2A adrenal medullary hyperplasias: histological and kinetic correlates
(John Wiley & Sons, 2000-06-26)
The relationship among histological features, cell kinetics, and clonality has not been studied in adrenal medullary hyperplasias (AMHs) and phaeochromocytomas (PCCs). Thirty-four PCCs (23 sporadic and 11 MEN-2A (multiple ...
Article
Influence of high glucose and advanced glycation end-products (ages) levels in human osteoblast-like cells gene expression
(2016)
Background: Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporotic fracture. Several factors have been identified as being potentially responsible for this risk, such as alterations in bone ...
Article
ASXL1 mutation as a surrogate marker in acute myeloid leukemia with myelodysplasia-related changes and normal karyotype
(Wiley Open Access, 2020)
Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) are poor outcome leukemias. Its diagnosis is based on clinical, cytogenetic, and cytomorphologic criteria, last criterion being sometimes difficult to ...
Article
Immunohistochemical profiling of the ultimobranchial remnants in the rat postnatal thyroid gland
(Wiley Periodicals, Inc., 2017-05-02)
Ultimobranchial (UB) remnants are a constant presence in the thyroid throughout rat postnatal life; however, the difficulty in identifying the most immature forms from the surrounding thyroid tissue prompted us to search ...
PhD Thesis
Article
The bitter side of epigenetics: variability and resistance to chemotherapy
(Future Medicine, 2021)
One of the major obstacles to the development of effective new cancer treatments and the main factor for the increasing number of clinical trial failures appears to be the paucity of accurate, reproducible and robust drug ...
Article
Spanish National Registry of Major Osteoporotic Fractures (REFRA) seen at Fracture Liaison Services (FLS): objectives and quality standards
(SPRINGER, 2022)
Summary REFRA-FLS is a new registry in Spain aimed at identifying individuals over 50 years of age with a fragility fracture. Using this registry, we found hip fracture is the most prevalent fracture. Treatment for ...
Article
Amitriptyline down-regulates coenzyme Q10 biosynthesis in lung cancer cells
(Elsevier, 2017)
Amitriptyline, a tricyclic antidepressant, has been proposed as an antitumoral drug in oxidative therapy. Its pro-apoptotic effects, mediated by high reactive oxygen species generation, have been already described. In ...
PhD Thesis
Article
Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients
(Impact Journals, 2017)
Wilms tumour (WT) is the most common renal tumour in children. Most WT patients respond to chemotherapy, but subsets of tumours develop resistance to chemotherapeutic agents, which is a major obstacle in their successful ...