ListarArtículos (Bioquímica y Biología Molecular) por materia "microglia"
Mostrando ítems 1-9 de 9
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Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model
(Impact Journals, LLC, 2015)Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative ...
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Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation
(Frontiers Media, 2018)Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, ...
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Galectin-3 is upregulated in frontotemporal dementia patients with subtype specificity
(Wiley, 2023-11)INTRODUCTION Neuroinflammation is a major contributor to the progression of frontotemporal dementia (FTD). Galectin-3 ...
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Microglial subtypes: diversity within the microglial community
(EMBO Press, 2019)Microglia are brain-resident macrophages forming the first active immune barrier in the central nervous system. They fulfill ...
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Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism
(BioMed Central, 2015)Background We have uncovered a caspase-dependent (caspase-8/caspase-3/7) signaling governing microglia activation and ...
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Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease
(Frontiers Media, 2018)The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role ...
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Relevance of chronic stress and the two faces of microglia in Parkinson’s disease
(rontiers Research Foundation, 2015)This review is aimed to highlight the importance of stress and glucocorticoids (GCs) in modulating the ...
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TET2 Regulates the Neuroinflammatory Response in Microglia
(Elsevier, 2019)Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune cells. Despite the central role for ...
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The Multifarious Role of Microglia in Brain Metastasis
(Frontiers Media, 2018)The immune landscape in brain metastasis is a very heterogeneous framework. Amongst a broad plethora of cells within the ...