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      Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease 

      Tayara, Khadija; Espinosa Oliva, Ana María; García Domínguez, Irene; Ismaiel, Afrah Abdul; Boza Serrano, Antonio; Deierborg, Tomas; Martínez de Pablos, Rocío; Machado de la Quintana, Alberto; Herrera Carmona, Antonio José; Venero Recio, José Luis (Frontiers Media, 2018)
      The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, ...
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      Galectin-3 is upregulated in frontotemporal dementia patients with subtype specificity 

      Borrego Écija, Sergi; Pérez Millan, Agnès; Antonell, Anna; Fort Aznar, Laura; Kaya Tilki, Elif; León Halcón, Alberto; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Boza Serrano, Antonio (Wiley, 2023-11)
      INTRODUCTION Neuroinflammation is a major contributor to the progression of frontotemporal dementia (FTD). Galectin-3 ...
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      Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism 

      Viceconte, Nikenza; Burguillos García, Miguel Ángel; Herrera Carmona, Antonio José; Martínez de Pablos, Rocío; Joseph, Bertrand; Venero Recio, José Luis (BioMed Central, 2015)
      Background We have uncovered a caspase-dependent (caspase-8/caspase-3/7) signaling governing microglia activation and ...
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      Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease 

      García Domínguez, Irene; Veselá, Karolina; García Revilla, Juan; Carrillo Jiménez, Alejandro; Roca Ceballos, María Angustias; Santiago Pavón, Martiniano; Martínez de Pablos, Rocío; Venero Recio, José Luis (Frontiers Media, 2018)
      The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role ...
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      Relevance of chronic stress and the two faces of microglia in Parkinson’s disease 

      Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Carrillo Jiménez, Alejandro; Oliva Martín, María José; García Revilla, Juan; García Quintanilla, Alberto; Martínez de Pablos, Rocío; Venero Recio, José Luis (rontiers Research Foundation, 2015)
      This review is aimed to highlight the importance of stress and glucocorticoids (GCs) in modulating the ...
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      TET2 Regulates the Neuroinflammatory Response in Microglia 

      Carrillo Jiménez, Alejandro; Ruiz Laza, Rocío; García Domínguez, Irene; García Revilla, Juan; Espinosa Oliva, Ana María; Venero Recio, José Luis; Burguillos García, Miguel Ángel; Tayara, Khadija (Elsevier, 2019)
      Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune cells. Despite the central role for ...