Listar Artículos (Bioquímica y Biología Molecular) por título
Mostrando ítems 174-193 de 223
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Reformulating Pro-Oxidant Microglia in Neurodegeneration
(MDPI, 2019)In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent ...
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Regional difference in inflammatory response to LPS-injection in the brain: Role of microglia cell density
(Elsevier, 2011)To elucidate whether density of cells could contribute to the extent of microglial activation, we performed in vitro assays ...
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Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia
(Nature Publishing Group, 2014)The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity ...
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Relevance of chronic stress and the two faces of microglia in Parkinson’s disease
(rontiers Research Foundation, 2015)This review is aimed to highlight the importance of stress and glucocorticoids (GCs) in modulating the ...
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Rhizospheric Organic Acids as Biostimulants: Monitoring Feedbacks on Soil Microorganisms and Biochemical Properties
(Frontiers Media, 2020-05-28)The biostimulant potential of three different organic acids (OAs) present in the rhizosphere, specifically lactic, oxalic, ...
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RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation
(Springer Nature, 2018)In this study, we took advantage of human-induced pluripotent stem cells (hiPSC) and CRISPR/Cas9 technology to investigate ...
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Sanitary impact evaluation of drinking water in storage reservoirs in Moroccan rural area
(King Saud University, 2017)In Morocco, storage reservoirs are particular systems of water supply in rural areas. These reservoirs are fed with rainwater ...
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Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion
(2016-12)Biotin is a water-soluble vitamin required for the function of carboxylases as well asfor the regulation of gene expression. ...
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Selective deletion of Caspase-3 gene in the dopaminergic system exhibits autistic-like behaviour
(Elsevier, 2021-01-10)Apoptotic caspases are thought to play critical roles in elimination of excessive and non-functional synapses and removal ...
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Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma
(Springer Nature, 2021)Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor of children and young adults in which the principal driver ...
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Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice
(BMC, 2020)Background The apolipoprotein E (APOE) gene exists in three isoforms in humans: APOE2, APOE3 and APOE4. APOE4 causes ...
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Should we open fire on microglia? Depletion models as tools to elucidate microglial role in health and alzheimer’s disease
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Microglia play a critical role in both homeostasis and disease, displaying a wide variety in terms of density, functional ...
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SIRT1 activation with neuroheal is neuroprotective but SIRT2 inhibition with AK7 is detrimental for disconnected motoneurons
(Springer Nature, 2018)Sirtuin 1 (SIRT1) activity is neuroprotective, and we have recently demonstrated its role in the retrograde degenerative ...
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Soluble phospho‑tau from Alzheimer’s disease hippocampus drives microglial degeneration
(Springer (part of Springer Nature): Springer Open Choice Hybrid Journals, 2016)The role of microglial cells in the development and progression of Alzheimer’s disease (AD) has not been elucidated. Here, ...
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Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke
(BioMed Central, 2016)Ischemic stroke (caused by thrombosis, embolism or vasoconstriction) lead to the recruitment and activation of immune cells ...
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STAT3-Mediated Astrocyte Reactivity Associated with Brain Metastasis Contributes to Neurovascular Dysfunction
(American Association for Cancer Research, 2020-10-26)Astrocytes are thought to play a pivotal role in coupling neural activity and cerebral blood flow. However, it has been ...
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Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases
(Springer Nature, 2021)Aging and fertility are two interconnected processes. From invertebrates to mammals, absence of the germline increases ...
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Stress and inflammation: a detrimental combination in the development of neurodegenerative disease
(Smart Science and Technology, 2014)Chronic stress accelerates the appearance of some neurodegenerative disorders, such as Alzheimer’s disease and Parkinson´s ...
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Stress Increases Vulnerability to Inflammation in the Rat Prefrontal Cortex
(Society for Neuroscience, 2006)Inflammation could be involved in some neurodegenerative disorders that accompany signs of inflammation. However, because ...
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Study of the biochemical activity and plant growth promoting bacteria in soils polluted with oxyfluorfen
(Taylor and Francis Group, 2023-08-13)There is currently a great deal of information available about the toxic effects of oxyfluorfen on soil biochemical activity ...