Buscar
Mostrando ítems 11-20 de 21
Artículo
Energy-dependent accumulation of norfloxacin and porin expression in clinical isolates of Klebsiella pneumoniae and relationship to extended-spectrum β-lactamase production
(American Society for Microbiology, 2002-12-01)
The relationships between porin deficiency, active efflux of fluoroquinolones, and extended-spectrum β-lactamase (ESBL) production were determined for 53 clinical isolates of Klebsiella pneumoniae. Thirty-two ESBL-positive ...
Artículo
Development of resistance during antimicrobial therapy caused by insertion sequence interruption of porin genes
(American Society for Microbiology, 1999-01-01)
We have demonstrated by using an in vitro approach that interruption of the OmpK36 porin gene by insertion sequences (ISs) is a common type of mutation that causes loss of porin expression and increased resistance to ...
Artículo
A multinational, preregistered cohort study of β-lactam/β-lactamase inhibitor combinations for treatment of bloodstream infections due to extended-spectrum-β-lactamase-producing enterobacteriaceae
(American Society for Microbiology, 2016-07-01)
The spread of extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) is leading to increased carbapenem consumption. Alternatives to carbapenems need to be investigated. We investigated whether ...
Artículo
Efficacy of cefepime and imipenem in experimental murine pneumonia caused by porin-deficient Klebsiella pneumoniae producing CMY-2 β-lactamase
(American Society for Microbiology, 2005-08-01)
Previous studies have shown decreased in vitro activity of zwitterionic cephalosporins and carbapenems against porin-deficient Klebsiella pneumoniae expressing a plasmid-mediated AmpC-type β-lactamase (PACBL). The in vitro ...
Artículo
Antimicrobial susceptibility pattern of Corynebacterium striatum
(American Society for Microbiology, 1996-11-01)
The in vitro activities of 16 antimicrobial agents against 86 strains of Corynebacterium striatum were evaluated by microdilution using cation- adjusted Mueller-Hinton broth. MICs at which 90% of strains were inhibited ...
Artículo
Energy-dependent accumulation of fluoroquinolones in quinolone- resistant Klebsiella pneumoniae strains
(American Society for Microbiology, 1998-07-01)
The intracellular accumulation of norfloxacin and perloxacin in Klebsiella pneumoniae was evaluated. The roles of lipopolysaccharide, capsule, and outer membrane proteins were not important for the intrabacterial accumulation ...
Artículo
Zinc eluted from siliconized latex urinary catheters decreases OprD expression, causing carbapenem resistance in Pseudomonas aeruginosa
(American Society for Microbiology, 2003-07-01)
The activities of carbapenems against Pseudomonas aeruginosa decreased in the presence of siliconized latex urinary catheters (SLUCs). This effect was associated with the loss of OprD. The zinc that eluted from SLUCs is ...
Artículo
Activities of ABT-773 against Listeria monocytogenes and coryneform bacteria of clinical interest
(American Society for Microbiology, 2003-04-01)
The in vitro activities of ABT-773 were evaluated against 15 Listeria monocytogenes strains and 196 coryneform bacteria isolated from clinical samples. One hundred percent of the L. monocytogenes strains were inhibited by ...
Artículo
Role of Klebsiella pneumoniae LamB porin in antimicrobial resistance
(American Society for Microbiology, 2003-10-01)
To investigate the contribution of LamB in Klebsiella pneumoniae antimicrobial resistance, we determined the MICs of various antibiotics and the frequency of mutation to increased cefoxitin or meropenem resistance of the ...
Artículo
Evaluation of three automated systems for susceptibility testing of enterobacteria containing qnrB, qnrS, and/or aac(6′)-Ib-cr
(American Society for Microbiology, 2011)
The accuracy of the MicroScan WalkAway, BD Phoenix, and Vitek-2 systems for susceptibility testing of quinolones and aminoglycosides against 68 enterobacteria containing qnrB, qnrS, and/or aac(6′)-Ib-cr was evaluated using ...