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Artículo
Uptake and intracellular activity of fluconazole in human polymorphonuclear leukocytes
(American Society for Microbiology, 1993-01-01)
The penetration of fluconazole into human polymorphonuclear leukocytes (PMNs) and tissue culture epithelial cells (McCoy) was evaluated. At different extracellular concentrations (0.5 to 10 mg/liter), fluconazole reached ...
Artículo
Intracellular penetration and activity of DX-619 in human polymorphonuclear leukocytes
(American Society for Microbiology, 2006-09-01)
The intracellular penetration and activity of DX-619 in human polymorphonuclear leukocytes have been evaluated. DX-619 reached intracellular concentrations 10 times higher than the extracellular concentrations reached. ...
Artículo
Uptake and intracellular activity of moxifloxacin in human neutrophils and tissue-cultured epithelial cells
(American Society for Microbiology, 1999-02-15)
The penetration by moxifloxacin of human neutrophils (polymorphonuclear leukocytes [PMN]) and tissue-cultured epithelial cells (McCoy cells) was evaluated by a fluorometric assay. At extracellular concentrations of 5 ...
Artículo
Uptake and intracellular activity of sparfloxacin in human polymorphonuclear leukocytes and tissue culture cells
(American Society for Microbiology, 1992-01-01)
The penetration of sparfloxacin into human neutrophils (PMN) and different tissue culture cells (HEp-2 and McCoy) was evaluated. The cellular to extracellular concentration ratios (C/E) of sparfloxacin were always higher ...
Artículo
Uptake and intracellular activity of linezolid in human phagocytes and nonphagocytic cells
(American Society for Microbiology, 2002-12-01)
The intracellular penetration and activity of linezolid in human polymorphonuclear leukocytes and tissue-cultured cells (McCoy) were evaluated. Linezolid reached intracellular concentrations slightly greater than extracellular ...
Artículo
Intracellular penetration and activity of BAY Y 3118 in human polymorphonuclear leukocytes
(American Society for Microbiology, 1994-01-01)
The penetration of a new quinolone (BAY Y 3118) into human polymorphonuclear leukocytes (PMNs) was evaluated by a fluorometric assay. The cellular concentration-to-extracellular concentration (C/E) ratio was higher than ...
Artículo
Intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes
(American Society for Microbiology, 2000-11-09)
The intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes (PMN) were evaluated. Gemifloxacin reached intracellular concentrations eight times higher than extracellular concentrations. ...
Artículo
Uptake and intracellular activity of an optically active ofloxacin isomer in human neutrophils and tissue culture cells
(American Society for Microbiology, 1990-01-01)
The penetration of an optically active ofloxacin isomer [(-)-ofloxacin] into human neutrophils and different tissue culture cells (HEp-2, McCoy, MDCK, and Vero) was studied and compared with that of ofloxacin by a fluorometric ...