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Artículo
The rem mutations in the ATP-binding groove of the Rad3/XPD helicase lead to Xeroderma pigmentosum-Cockayne Syndrome-like phenotypes
(Public Library of Science, 2014)
The eukaryotic TFIIH complex is involved in Nucleotide Excision Repair and transcription initiation. We analyzed three yeast mutations of the Rad3/XPD helicase of TFIIH known as rem (recombination and mutation phenotypes). ...
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The Sister-Chromatid Exchange Assay in Human Cells
(Humana, 2020)
The semiconservative nature of DNA replication allows the differential labeling of sister chromatids that isthe fundamental requirement to perform the sister-chromatid exchange (SCE) assay. SCE assay is apowerful technique ...
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Biosíntesis de carotenoides en hongos
(Terracota, 2017)
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Un ciclo de mejora docente para estudiar Evolución Molecular
(Universidad de Sevilla, 2022)
En asignaturas de genética, aprender a resolver problemas es esencial para fortalecer la integración de los conceptos que se imparten en las clases teóricas. De hecho, el modelo metodológico tradicional suele basarse en ...
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Detection of DNA Double-Strand Breaks byγ-H2AX Immunodetection
(Humana, 2020)
DNA double-strand breaks (DSBs) are the most deleterious type of DNA damage and a cause of geneticinstability as they can lead to mutations, genome rearrangements, or loss of genetic material when notproperly repaired. ...
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Coupling Between Messenger RNA Synthesis and Degradation during Genome Expression
(Fidetia, 2015)
Genome expression involves the synthesis of messenger RNA (mRNA), a short lived molecule whose translation directs the synthesis of cellular proteins and that is subject to degradation after the translation process. Up ...