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Artículo
Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery
(Rockefeller University Press, 2009)
The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in mammalian cells, binds the tumor suppressor protein BRCA2. Here, we describe a new function for yeast ...
Artículo
Metabolite repression and inducer exclusion in the proline utilization gene cluster of Aspergillus nidulans
(American Society for Microbiology, 2000)
The clustered prnB, prnC, and prnD genes are repressed by the simultaneous presence of glucose and ammonium. A derepressed mutation inactivating a CreA-binding site acts in cis only on the permease gene (prnB) while ...
Artículo
The Phycomyces madA gene encodes a blue-light photoreceptor for phototropism and other light responses
(National Academy of Sciences, 2006)
Phycomyces blakesleeanus is a filamentous zygomycete fungus that produces striking elongated single cells that extend up to 10 cm into the air, with each such sporangiophore supporting a sphere containing the spores for ...
Artículo
Glucose Uptake in Trichoderma harzianum: Role of gtt1
(American Society for Microbiology, 2003-08)
Using a differential display technique, the gene gtt1, which codes for a high-affinity glucose transporter, has been cloned from the mycoparasite fungus Trichoderma harzianum CECT 2413. The deduced protein sequence of the ...
Artículo
Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin
(Elsevier, 2009)
Salmonella enterica encodes two virulence-related type III secretion systems in Salmonella pathogenicity islands 1 and 2, respectively. These systems mediate the translocation of protein effectors into the eukaryotic host ...
Artículo
The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability
(American Society for Cell Biology, 2008)
The eukaryotic THO/TREX complex, involved in mRNP biogenesis, plays a key role in the maintenance of genome integrity in yeast. mRNA export factors such as Thp1-Sac3 also affect genome integrity, but their mutations have ...
Artículo
Biocontrol mechanisms of Thrichoderma strains
(Sociedad Española de MicrobiologÍa, 2004)
The genus Trichoderma comprises a great number of fungal strains that act as biological control agents, the antagonistic properties of which are based on the activation of multiple mechanisms. Trichoderma strains exert ...
Artículo
Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole-genome duplication
(Public Library of Science, 2009)
Rhizopus oryzae is the primary cause of mucormycosis, an emerging, life-threatening infection characterized by rapid angioinvasive growth with an overall mortality rate that exceeds 50%. As a representative of the paraphyletic ...
Artículo
Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants
(American Society for Microbiology, 2006)
THO is a protein complex that functions in cotranscriptional mRNP formation. Yeast THO1 and SUB2 (Saccharomyces cerevisiae) were identified as multicopy suppressors of the expression defects of the hpr1 mutant of THO. ...
Artículo
New findings of Neurospora in Europe and comparisons of diversity in temperate climates on continental scales
(Allen Press Inc, 2006)
The life cycles of the conidiating species of Neurospora are adapted to respond to fire, which is reflected in their natural history. Neurospora is found commonly on burned vegetation from the tropic and subtropical regions ...