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Artículo
Final pre-40s maturation depends on the functional integrity of the 60s subunit ribosomal protein l3
(Public Library of Science, 2014)
Ribosomal protein L3 is an evolutionarily conserved protein that participates in the assembly of early pre-60S particles. We report that the rpl3[W255C] allele, which affects the affinity and function of translation ...
Artículo
The dedicated chaperone acl4 escorts ribosomal protein rpl4 to its nuclear pre-60s assembly site
(Public Library of Science, 2015)
Ribosomes are the highly complex macromolecular assemblies dedicated to the synthesis of all cellular proteins from mRNA templates. The main principles underlying the making of ribosomes are conserved across eukaryotic ...
Artículo
Dynamics of the putative RNA helicase spb4 during ribosome assembly insaccharomyces cerevisiae
(American Society for Microbiology, 2011)
Spb4 is a putative ATP-dependent RNA helicase that is required for proper processing of 27SB pre-rRNAs and therefore for 60S ribosomal subunit biogenesis. To define the timing of association of this protein with preribosomal ...
Artículo
A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae
(Oxford University Press, 2021)
Proteostasis needs to be tightly controlled to meet the cellular demand for correctly de novo folded proteins and to avoid protein aggregation. While a coupling between translation rate and co-translational folding, likely ...
Artículo