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Artículo
Conjugal transfer of the Salmonella enterica virulence plasmid in the mouse intestine
(American Society for Microbiology, 2008)
BALB/c mice were infected with two Salmonella enterica serovar Typhimurium strains, one of which lacked the virulence plasmid. Transconjugants were found at high frequencies in the mouse feces and at low frequencies in the ...
Artículo
Interactions between Bacteria and Bile Salts in the Gastrointestinal and Hepatobiliary Tracts
(Frontiers Media, 2017)
Bile salts and bacteria have intricate relationships. The composition of the intestinal pool of bile salts is shaped by bacterial metabolism. In turn, bile salts play a role in intestinal homeostasis by controlling the ...
Artículo
Roles of the outer membrane protein asmA of Salmonella enterica in the control of marRAB expression and invasion of epithelial cells
(American Society for Microbiology, 2009)
A genetic screen for suppressors of bile sensitivity in DNA adenine methylase (dam) mutants of Salmonella enterica serovar Typhimurium yielded insertions in an uncharacterized locus homologous to the Escherichia coli asmA ...
Artículo
Regulation of bistability in the std fimbrial operon of Salmonella enterica by DNA adenine methylation and transcription factors HdfR, StdE and StdF
(Oxford Academic, 2019-09-05)
Bistable expression of the Salmonella enterica std operon is controlled by an AND logic gate involving three transcriptional activators: the LysR-type factor HdfR and the StdE and StdF regulators encoded by the std operon ...
Artículo
Single cell analysis of bistable expression of pathogenicity island 1 and the flagellar regulon in Salmonella enterica
(MDPI, 2021-01)
Bistable expression of the Salmonella enterica pathogenicity island 1 (SPI-1) and the flagellar network (Flag) has been described previously. In this study, simultaneous monitoring of OFF and ON states in SPI-1 and in the ...
Artículo
Genome-Wide Identification and Expression Analysis of SOS Response Genes in Salmonella enterica Serovar Typhimurium
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
A bioinformatic search for LexA boxes, combined with transcriptomic detection of loci responsive to DNA damage, identified 48 members of the SOS regulon in the genome of Salmonella enterica serovar Typhimurium. Single cell ...
Artículo
LeuO is a global regulator of gene expression in Salmonella enterica serovar Typhimurium
(Wiley-Blackwell, 2012)
We report the first investigation of the binding of the Salmonella enterica LeuO LysR-type transcription regulator to its genomic targets in vivo. Chromatin-immunoprecipitation-on-chip identified 178 LeuO binding sites on ...
Artículo
Contribution of DNA adenine methylation to gene expression heterogeneity in Salmonella enterica
(Oxford University Press, 2020)
Expression of Salmonella enterica loci harboring undermethylated GATC sites at promoters or regulatory regions was monitored by single cell analysis. Cell-to-cell differences in expression were detected in ten such loci ...
Artículo
Regulation of igaA and the rcs system by the mvia response regulator in salmonella enterica
(American Society for Microbiology, 2009)
IgaA is a membrane protein that prevents overactivation of the Rcs regulatory system in enteric bacteria. Here we provide evidence that igaA is the first gene in a 70-dependent operon of Salmonella enterica serovar Typhimurium ...
Artículo
Mutational and non mutational adaptation of Salmonella enterica to the gall bladder
(Natural Research, 2019)
During systemic infection of susceptible hosts, Salmonella enterica colonizes the gall bladder, which contains lethal concentrations of bile salts. Recovery of Salmonella cells from the gall bladder of infected mice yields ...