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Mostrando ítems 1-10 de 28
Artículo
Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle
(Springer Nature, 2023)
Skeletal muscle is more resilient to ischemia-reperfusion injury than other organs. Tissue specific post-translational modifications of cytochrome c (Cytc) are involved in ischemia-reperfusion injury by regulating mitochondrial ...
Artículo
A common signalosome for programmed cell death in humans and plants
(Nature Publishing Group, 2014)
Artículo
Editorial: Weak interactions in molecular machinery volume II
(Frontiers Media S.A., 2023)
Artículo
The sequence selectivity of KSRP explains its flexibility in the recognition of the RNA targets
(Oxford University Press, 2008)
K-homology (KH) splicing regulator protein (KSRP) is a multi-domain RNA-binding protein that regulates different steps of mRNA metabolism, from mRNA splicing to mRNA decay, interacting with a broad range of RNA sequences. ...
Artículo
Cytochrome c signalosome in mitochondria
(Springer, 2011)
Cytochrome c delicately tilts the balance between cell life (respiration) and cell death (apoptosis). Whereas cell life is governed by transient electron transfer interactions of cytochrome c inside the mitochondria, the ...
Artículo
Nicotinamide N-methyltransferase (NNMT) regulates the glucocorticoid signaling pathway during the early phase of adipogenesis
(Springer Nature, 2023-05-22)
Obesity is associated with adipose tissue dysfunction through the differentiation and expansion of pre-adipocytes to adipocytes (hyperplasia) and/or increases in size of pre-existing adipocytes (hypertrophy). A cascade of ...
Artículo
The cytochrome f–plastocyanin complex as a model to study transient interactions between redox proteins
(Wiley, 2012)
Transient complexes, with a lifetime ranging between microseconds and seconds, are essential forbiochemical reactions requiring a fast turnover. That is the case of the interactions between proteinsengaged in electron ...
Artículo
Structure of the Complex between Plastocyanin and Cytochrome f from the Cyanobacterium Nostoc sp. PCC 7119 as Determined by Paramagnetic NMR
(Elsevier, 2005)
The complex between cytochrome f and plastocyanin from the cyanobacterium Nostoc has been characterized by NMR spectroscopy. The binding constant is 16 mm–1, and the lifetime of the complex is much less than 10 ms. ...
Artículo
Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding
(Nature Research, 2009)
The AU-rich element (ARE)-mediated mRNA-degradation activity of the RNA binding K-homology splicing regulator protein (KSRP) is regulated by phosphorylation of a serine within its N-terminal KH domain (KH1). In the cell, ...
Artículo
Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism
(Elsevier, 2023)
Neddylation is a post-translational mechanism that adds a ubiquitin-like protein, namely neural precursor cell expressed developmentally downregulated protein 8 (NEDD8). Here, we show that neddylation in mouse liver is ...