Buscar
Mostrando ítems 1-4 de 4
Artículo
A protocol to enrich in undifferentiated cells from neuroblastoma tumor tissue samples and cell lines
(Cell Press, 2022)
The existence of a subpopulation of undifferentiated cells with stem-like properties has been suggested in neuroblastoma tumors, but a definitive biomarker for their successful isolation is missing. Here we describe an in ...
Artículo
MDC1 maintains active elongation complexes of RNA polymerase II
(Elsevier, 2023)
The role of MDC1 in the DNA damage response has been extensively studied; however, its impact on other cellular processes is not well understood. Here, we describe the role of MDC1 in transcription as a regulator of RNA ...
Artículo
Anti-tumour activity of Digitalis purpurea L. subsp. heywoodii
(Georg Thieme Verlag, 2003)
Recent research has shown the anticancer effects of digitalis compounds suggesting their possible use in medical oncology. Four extracts obtained from the leaves of Digitalis purpurea subsp. heywoodii have been assessed ...
Artículo
CD44-high neural crest stem-like cells are associated with tumour aggressiveness and poor survival in neuroblastoma tumours
(Elsevier, 2019)
BACKGROUND: Neuroblastoma is a paediatric tumour originated from sympathoadrenal precursors and characterized by its heterogeneity and poor outcome in advanced stages. Intra-tumoral cellular heterogeneity has emerged as ...