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Artículo
Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast
(Company of Biologists Ltd, 2014)
Lipids synthesized at the endoplasmic reticulum (ER) are delivered to the Golgi by vesicular and non-vesicular pathways. ER-to-Golgi transport is crucial for maintaining the different membrane lipid composition and identities ...
Artículo
Impact of Sphingolipids on Protein Membrane Trafficking
(Elsevier, 2023)
Membrane trafficking is essential to maintain the spatiotemporal control of protein and lipid distribution within membrane systems of eukaryotic cells. To achieve their functional destination proteins are sorted and ...
Artículo
Quality-controlled ceramide-based GPI-anchored protein sorting into selective ER exit sites
(Elsevier, 2022)
Glycosylphosphatidylinositol-anchored proteins (GPI-APs) exit the endoplasmic reticulum (ER) through a specialized export pathway in the yeast Saccharomyces cerevisiae. We have recently shown that a very-long acyl chain ...
Artículo
Protein sorting upon exit from the endoplasmic reticulum dominates Golgi biogenesis in budding yeast
(Willey, 2023-02-24)
Cells sense and control the number and quality of their organelles, but the underlying mechanisms of this regulation are not understood. Our recent research in the yeast Saccharomyces cerevisiae has shown that long acyl ...