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Mostrando ítems 1-10 de 13
Artículo
A microRNA expression signature of the postprandial state in response to a high-saturated-fat challenge
(Elsevier, 2018)
The postprandial hypertriglyceridemia is an important and largely silent disturbance involved in the genesis of numerous pathological conditions. Exaggerated and prolonged states of postprandial hypertriglyceridemia are ...
Artículo
El papel del docente en un aula hospitalaria de oncología pediátrica
(Universidad Andina Simón Bolívar, 2018-08)
Mostramos en este estudio los resultados de un trabajo de observación indirecta de la labor de los docentes de las aulas hospitalarias del área de oncología pediátrica del Hospital Universitario Virgen del Rocío de la ...
Artículo
In Vitro Toxicity of Asparagus Saponins in Distinct Multidrug-Resistant Colon Cancer Cells
(Wiley-Blackwell, 2018)
Colorectal cancer is the third most common cancer in the world. Many efforts have focused on finding natural molecules with potential chemo-preventive activity due to their low toxicity compared to synthetic drugs. However, ...
Artículo
Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside
(Wiley, 2018)
Several clinically useful anticancer drugs selectively kill cancer cells by inducing DNA damage; the genomic instability and DNA repair defects of cancer cells make them more vulnerable than normal cells to the cytotoxicity ...
Artículo
The Cockayne syndrome protein B is involved in the repair of 5-AZA-2′-deoxycytidine-induced DNA lesions
(Impact Journals, 2018)
The Cockayne Syndrome Protein B (CSB) plays an essential role in Transcription-Coupled Nucleotide Excision Repair (TC-NER) by recruiting repair proteins once transcription is blocked with a DNA lesion. In fact, CSB-deficient ...
Artículo
Nintedanib decreases muscle fibrosis and improves muscle function in a murine model of dystrophinopathy
(Nature Publishing Group, 2018)
Duchenne muscle dystrophy (DMD) is a genetic disorder characterized by progressive skeletal muscle weakness. Dystrophin deficiency induces instability of the sarcolemma during muscle contraction that leads to muscle necrosis ...
Artículo
Author Correction: Scutoids are a geometrical solution to three-dimensional packing of epithelia
(Nature Research, 2018)
Artículo
Unsaponifiable fraction isolated from grape (vitis vinifera l.) seed oil attenuates oxidative and inflammatory responses in human primary monocytes
(Royal Society of Chemistry, 2018)
Grape (Vitis vinifera L.) seed has well-known potential for production of oil as a byproduct of winemaking and is a rich source of bioactive compounds. Herein, we report that the unsaponifiable fraction (UF) isolated from ...
Artículo
Sensing Cell-Culture Assays with Low-Cost Circuitry
(Nature Publishing Group, 2018)
An alternative approach for cell-culture end-point protocols is proposed herein. This new technique is suitable for real-time remote sensing. It is based on Electrical Cell-substrate Impedance Spectroscopy (ECIS) and employs ...
Tesis Doctoral
Un subgrupo de isoformas de los receptores de lipoforinas de Drosophila melanogaster interacciona con distintas afinidades con las lipoproteinas lipoforina y LTP en la membrana plasmática, mediando así la adquisición celular de lípidos neutros.
(2018-07-11)
El estilo de vida sedentario sumado a nuevos hábitos de alimentación están generando a nivel mundial un incesante aumento de enfermedades relacionadas con el metabolismo lipídico y sus complicaciones, como por ejemplo la ...