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Mostrando ítems 641-650 de 669
Artículo
Pharmacological Chaperones for the Treatment of α-Mannosidosis
(American Chemical Society, 2019)
α-Mannosidosis (AM) results from deficient lysosomal α-mannosidase (LAMAN) activity and subsequent substrate accumulation in the lysosome, leading to severe pathology. Many of the AM-causative mutations compromise enzyme ...
Artículo
Hydrolytic degradation of D-mannitol-based polyurethanes
(Elsevier, 2018)
The capacity of redox D-mannitol-based polyurethanes to modulate the glutathione response under physiological conditions, as well as their effectiveness for sustained and site-specific drug release in the gastrointestinal ...
Artículo
Enriching User Reviews Through An Opinion Extraction System
(Sociedad Española para el Procesamiento del Lenguaje Natural (SEPLN), 2015)
Web sites based on User-Generated Content (UGC) have a potentially valuable applicability in a number of elds. In this work we carry out a study of the usefulness of these systems from the point of view of detecting the ...
Artículo
σ-Silane Platinum(II) Complexes as Intermediates in C−Si Bond-Coupling Processes
(Wiley, 2019)
Platinum complexes [Pt(NHC’)(NHC)][BArF] (NHC’ denotes the cyclometallated N-heterocyclic carbene ligand, NHC) react with primary silanes RSiH3 leading to the cyclometallated platinum(II) silyl complexes [Pt(NHC-SiHR’ ...
Artículo
Biomonitoring of 21 endocrine disrupting chemicals in human hair samples using ultra-high performance liquid chromatography-tandem mass spectrometry
(Elsevier, 2017-02)
Rapid industrial growth has increased human exposure to a large variety of chemicals with adverse health effects. These industrial chemicals are usually present in the environment, foods, beverages, clothes and personal ...
Artículo
The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity article
(Springer Nature [academic journals on nature.com, 2018)
HMG20A (also known as iBRAF) is a chromatin factor involved in neuronal differentiation and maturation. Recently small nucleotide polymorphisms (SNPs) in the HMG20A gene have been linked to type 2 diabetes mellitus (T2DM) ...
Artículo
The role of carbon nanotubes on the stability of tetragonal zirconia polycrystals
(Elsevier, 2018-10)
The effect of single walled carbon nanotubes (SWNT) at zirconia grain boundaries on the stability of a tetragonal zirconia polycrystalline matrix has been explored in as–sintered composites and after low–temperature ...
Artículo
Carbon Dioxide as a Traceless Caramelization Promotor: Preparation of Prebiotic Difructose Dianhydrides (DFAs)-Enriched Caramels from D-Fructose
(American Chemical Society, 2017)
Activation of a concentrated solution of D-fructose with carbonic acid, generated from carbon dioxide, induces the formation of difructose dianhydrides (DFAs) and their glycosylated derivatives (glycosyl-DFAs), a family ...
Artículo
Clustering categories in support vector machines
(Elsevier, 2016-02)
The support vector machine (SVM) is a state-of-the-art method in supervised classification. In this paper the Cluster Support Vector Machine (CLSVM) methodology is proposed with the aim to increase the sparsity of the SVM ...
Artículo
Effect of the crystal chemistry on the hydration mechanism of swelling micas
(Elsevier, 2017)
Swelling and dehydration under minor changes in temperature and water vapor pressure is an important property that clays and clay minerals exhibit. In particular, their interlayer space, the solid-water interface and the ...