dc.creator | Guzzi, Cinzia | es |
dc.creator | Muñoz García, Juan Carlos | es |
dc.creator | Enriquez Navas, Pedro Miguel | es |
dc.creator | Rojo, Javier | es |
dc.creator | Angulo Álvarez, Jesús | es |
dc.creator | Nieto, Pedro M. | es |
dc.date.accessioned | 2020-06-15T08:35:37Z | |
dc.date.available | 2020-06-15T08:35:37Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Guzzi, C., Muñoz García, J.C., Enriquez Navas, P.M., Rojo, J., Angulo Álvarez, J. y Nieto, P.M. (2013). NMR studies on carbohydrate interactions with DC-SIGN towards a quantitative STD analysis. Pure and Applied Chemistry, 85 (9), 1771-1787. | |
dc.identifier.issn | 0033-4545 (impreso) | es |
dc.identifier.issn | 1365-3075 (electrónico) | es |
dc.identifier.uri | https://hdl.handle.net/11441/97800 | |
dc.description.abstract | The recent introduction of saturation transfer difference (STD) NMR has increased
the tools for the study of protein–carbohydrate complexes. This is useful when it is combined
with transfer nuclear Overhauser enhancement spectroscopy (NOESY) measurement, or
when it is interpreted using the expected calculated values of transference, yielding additional, very valuable information for the study of this type of complex.
The objective of this work is to cover the advances of the STD technique as exemplified by the investigations of DC-SIGN (dendritic cell-specific ICAM-3 grabbing non-integrin) recognition by simple carbohydrates or mimics of them, based on structures containing
a terminal mannose or fucose. We also will discuss the methods for quantification of the STD
values based on the initial growing rates with the saturation time. | es |
dc.format | application/pdf | es |
dc.format.extent | 17 p. | es |
dc.language.iso | eng | es |
dc.publisher | De Gruyter | es |
dc.relation.ispartof | Pure and Applied Chemistry, 85 (9), 1771-1787. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Carbohydrates | es |
dc.subject | Lectin | es |
dc.subject | Molecular interactions | es |
dc.subject | Molecular recognition | es |
dc.subject | NMR | es |
dc.title | NMR studies on carbohydrate interactions with DC-SIGN towards a quantitative STD analysis | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química orgánica | es |
dc.relation.publisherversion | https://doi.org/10.1351/pac-con-12-11-14 | es |
dc.identifier.doi | 10.1351/pac-con-12-11-14 | es |
dc.journaltitle | Pure and Applied Chemistry | es |
dc.publication.volumen | 85 | es |
dc.publication.issue | 9 | es |
dc.publication.initialPage | 1771 | es |
dc.publication.endPage | 1787 | es |