dc.creator | Galbis Fuster, Elsa | es |
dc.creator | Paz Báñez, María Violante de | es |
dc.creator | Iglesias, N. | es |
dc.creator | Lucas Rodríguez, Ricardo | es |
dc.creator | Galbis Pérez, Juan Antonio | es |
dc.date.accessioned | 2019-10-07T11:19:21Z | |
dc.date.available | 2019-10-07T11:19:21Z | |
dc.date.issued | 2017-04 | |
dc.identifier.citation | Galbis Fuster, E., Paz Báñez, M.V.d., Iglesias, N., Lucas Rodríguez, R. y Galbis Pérez, J.A. (2017). pH-Responsive Polymeric Nanoparticles as Drug Delivery Systems. Journal of Drug Design and Research, 4 (4), 1047. | |
dc.identifier.issn | 2379-089X | es |
dc.identifier.uri | https://hdl.handle.net/11441/89467 | |
dc.description.abstract | Micelles are excellent devices to be used as controlled drug delivery systems since they
exhibit the ability to protect the drug or encapsulated substance from the routes of degradation
until they reach the site of action: moreover, they can pass through biological barriers and
reach intracellular compartments. In addition, when a drug is administered and released from
the dosage form, the kinetic behavior of the drug depends largely on their chemical structure.
However, when the drug is immersed at the core of a NP, the physicochemical properties that
actually affect the distribution of the drug in the body are those from the latter. As a result, this
approach controls drug release, diminishing side effects and increasing therapeutic rates. In the
present work novel smart micelles have been prepared and tested as drug delivery systems | es |
dc.description.sponsorship | Ministerio de Economía y Competitividad-Grant MAT2016-77345-C3-2-P | es |
dc.description.sponsorship | Junta de Andalucía-Grant P12-FQM-1553 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | JSciMed Central | es |
dc.relation.ispartof | Journal of Drug Design and Research, 4 (4), 1047. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Smart polymers | es |
dc.subject | Nanoparticles | es |
dc.subject | Drug loading | es |
dc.subject | Pilocarpine | es |
dc.title | pH-Responsive Polymeric Nanoparticles as Drug Delivery Systems | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química Orgánica y Farmacéutica | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Ingeniería Química | es |
dc.relation.projectID | Grant MAT2016-77345-C3-2-P | es |
dc.relation.projectID | Grant P12-FQM-1553 | es |
dc.relation.publisherversion | http://www.jscimedcentral.com/DrugDesign/vol4issue4.php | es |
idus.format.extent | 5 p. | es |
dc.journaltitle | Journal of Drug Design and Research | es |
dc.publication.volumen | 4 | es |
dc.publication.issue | 4 | es |
dc.publication.initialPage | 1047 | es |