dc.creator | Velasco Forte, Mari Nieves | es |
dc.creator | Valverde, Israel | es |
dc.creator | Prabhu, Nanda | es |
dc.creator | Correia, Teresa | es |
dc.creator | Narayan, Srinivas Ananth | es |
dc.creator | Bell, Aaron | es |
dc.creator | Mathur, Sujeev | es |
dc.creator | Razavi, Reza | es |
dc.creator | Hussain, Tarique | es |
dc.creator | Pushparajah, Kuberan | es |
dc.creator | Henningsson, Markus | es |
dc.date.accessioned | 2019-05-28T07:27:54Z | |
dc.date.available | 2019-05-28T07:27:54Z | |
dc.date.issued | 2019-02 | |
dc.identifier.citation | Velasco Forte, M.N., Valverde, I., Prabhu, N., Correia, T., Narayan, S.A., Bell, A.,...,Henningsson, M. (2019). Visualization of coronary arteries in paediatric patients using whole-heart coronary magnetic resonance angiography: comparison of image-navigation and the standard approach for respiratory motion compensation. Journal of Cardiovascular Magnetic Resonance, 21 (1), 13-1-13-9. | |
dc.identifier.issn | 1097-6647 | es |
dc.identifier.issn | 1532-429X | es |
dc.identifier.uri | https://hdl.handle.net/11441/86880 | |
dc.description.abstract | Aims: To investigate the use of respiratory motion compensation using image-based navigation (iNAV) with
constant respiratory efficiency using single end-expiratory thresholding (CRUISE) for coronary magnetic resonance
angiography (CMRA), and compare it to the conventional diaphragmatic navigator (dNAV) in paediatric patients
with congenital or suspected heart disease.
Methods: iNAV allowed direct tracking of the respiratory heart motion and was generated using balanced steady
state free precession startup echoes. Respiratory gating was achieved using CRUISE with a fixed 50% efficiency.
Whole-heart CMRA was acquired with 1.3mm isotropic resolution. For comparison, CMRA with identical imaging
parameters were acquired using dNAV. Scan time, visualization of coronary artery origins and mid-course, imaging
quality and sharpness was compared between the two sequences.
Results: Forty patients (13 females; median weight: 44 kg; median age: 12.6, range: 3 months–17 years) were
enrolled. 25 scans were performed in awake patients. A contrast agent was used in 22 patients. The scan time was
significantly reduced using iNAV for awake patients (iNAV 7:48 ± 1:26 vs dNAV 9:48 ± 3:11, P = 0.01) but not for
patients under general anaesthesia (iNAV = 6:55 ± 1:50 versus dNAV = 6:32 ± 2:16; P = 0.32). In 98% of the cases,
iNAV image quality had an equal or higher score than dNAV. The visual score analysis showed a clear difference,
favouring iNAV (P = 0.002). The right coronary artery and the left anterior descending vessel sharpness was
significantly improved (iNAV: 56.8% ± 10.1% vs dNAV: 53.7% ± 9.9%, P < 0.002 and iNAV: 55.8% ± 8.6% vs dNAV:
53% ± 9.2%, P = 0.001, respectively). Conclusion: iNAV allows for a higher success-rate and clearer depiction of the mid-course of coronary arteries in
paediatric patients. Its acquisition time is shorter in awake patients and image quality score is equal or superior to
the conventional method in most cases. | es |
dc.description.sponsorship | Medical Engineering at King’s College London WT 088641/Z/09/Z | es |
dc.description.sponsorship | BHF Centre of Excellence RE/08/03 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Springer Nature | es |
dc.relation.ispartof | Journal of Cardiovascular Magnetic Resonance, 21 (1), 13-1-13-9. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Coronary magnetic resonance angiography | es |
dc.subject | Respiratory motion compensation | es |
dc.subject | Coronary artery disease | es |
dc.subject | Image-based navigation | es |
dc.title | Visualization of coronary arteries in paediatric patients using whole-heart coronary magnetic resonance angiography: comparison of image-navigation and the standard approach for respiratory motion compensation | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Instituto de Biomedicina de Sevilla (IBIS) | es |
dc.relation.projectID | RE/08/03 | es |
dc.relation.projectID | WT 088641/Z/09/Z | es |
dc.relation.publisherversion | https://doi.org/10.1186/s12968-019-0525-8 | es |
dc.identifier.doi | 10.1186/s12968-019-0525-8 | es |
idus.format.extent | 9 p. | es |
dc.journaltitle | Journal of Cardiovascular Magnetic Resonance | es |
dc.publication.volumen | 21 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 13-1 | es |
dc.publication.endPage | 13-9 | es |