Bioactive Coatings on Porous Titanium for Biomedical Applications
Ternero Fernández, Fátima
Rodríguez-Ortiz, José Antonio
Boccaccini, Aldo R.
Lebrato Martínez, Julián
Torres Hernández, Yadir
|Department||Universidad de Sevilla. Departamento de Ingeniería y Ciencia de los Materiales y del Transporte
Universidad de Sevilla. Departamento de Ingeniería Química
|Abstract||Commercial pure titanium is a recognized and accepted material for cortical bone tissue substitution. However, stress-shielding phenomena and lack of osseointegration result in significant limitations. This work is focused ...
Commercial pure titanium is a recognized and accepted material for cortical bone tissue substitution. However, stress-shielding phenomena and lack of osseointegration result in significant limitations. This work is focused on the achievement of an effective solution for both problems via fabrication of porous titanium substrates coated with bioactive glass. Substrates were obtained through the space holder technique giving values of stiffness and yield strength compatible with cortical bone tissue to reduce the stress-shielding phenomenon. Titanium substrates were coated with different number of layers of bioactive glass 45S5 by dripping sedimentation. The substrates porosity was characterized by different techniques. Ultrasound, compression and micro-mechanical testing were used for mechanical properties evaluation. After substrates coating, the infiltration ability, coating homogeneity and structural integrity (chipping and cracking) were evaluated for each coating layer. The chemical composition of coating and phases were studied before and after in vitro tests in Simulated Body Fluid. The results showed more homogenous coating, adherence and greater hydroxyapatite growth for the tri-layer system in both dense and porous samples. Besides, the relation of Ca/P was closed to that of stoichiometric hydroxyapatite in the human body. The coated porous titanium could be potentially used in load bearing partial implants with improved osseointegration.
|Citation||Domínguez-Trujillo, C., Ternero Fernández, F., Rodríguez-Ortiz, J.A., Heise, S., Boccaccini, A.R., Lebrato Martínez, J. y Torres Hernández, Y. (2018). Bioactive Coatings on Porous Titanium for Biomedical Applications. Surface and Coatings Technology, 349, 584-592.|