Presentation
Practical Characterization of Cell-Electrode Electrical Models in Bio-Impedance Assays
Author/s | Serrano, Juan A.
Pérez García, Pablo Maldonado-Jacobi, Andrés Martín Rubio, María Esther Olmo Fernández, Alberto Daza Navarro, María Paula Huertas Sánchez, Gloria Yúfera García, Alberto |
Department | Universidad de Sevilla. Departamento de Tecnología Electrónica Universidad de Sevilla. Departamento de Biología Celular |
Publication Date | 2018 |
Deposit Date | 2018-06-22 |
Published in |
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ISBN/ISSN | 978-989-758-277-6 |
Abstract | This paper presents the fitting process followed to adjust the parameters of the electrical model associated to a cell-electrode system in Electrical Cell-substrate Impedance Spectroscopy (ECIS) technique, to the experimental ... This paper presents the fitting process followed to adjust the parameters of the electrical model associated to a cell-electrode system in Electrical Cell-substrate Impedance Spectroscopy (ECIS) technique, to the experimental results from cell-culture assays. A new parameter matching procedure is proposed, under the basis of both, mismatching between electrodes and time-evolution observed in the system response, as consequence of electrode fabrication processes and electrochemical performance of electrode-solution interface, respectively. The obtained results agree with experimental performance, and enable the evaluation of the cell number in a culture, by using the electrical measurements observed at the oscillation parameters in the test circuits employed. |
Funding agencies | Ministerio de Economía y Competitividad (MINECO). España |
Project ID. | TEC2013-46242-C3-1-P |
Citation | Serrano, J.A., Pérez García, P., Maldonado, A., Martín Rubio, M.E., Olmo Fernández, A., Daza Navarro, M.P.,...,Yúfera García, A. (2018). Practical Characterization of Cell-Electrode Electrical Models in Bio-Impedance Assays. En BIODEVICES 2018: 11th International Joint Conference on Biomedical Engineering Systems and Technologies (100-108), Funchal, Madeira, Portugal: ScitePress Digital Library. |
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