dc.creator | Briones Moreno, Asier | es |
dc.creator | Hernández García, Jorge | es |
dc.creator | Vargas Chávez, Carlos | es |
dc.creator | Romero Campero, Francisco José | es |
dc.creator | Romero Rodríguez, José María | es |
dc.creator | Valverde Albacete, Federico | es |
dc.creator | Blázquez, Miguel A. | es |
dc.date.accessioned | 2017-12-14T14:23:32Z | |
dc.date.available | 2017-12-14T14:23:32Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Briones Moreno, A., Hernández García, J., Vargas Chávez, C., Romero Campero, F.J., Romero Rodríguez, J.M., Valverde Albacete, F. y Blázquez, M.A. (2017). Evolutionary Analysis of DELLA-Associated Transcriptional Networks. Frontiers in Plant Science, 8, 626-1-626-11. | |
dc.identifier.issn | 1664-462X (electrónico) | es |
dc.identifier.uri | http://hdl.handle.net/11441/67626 | |
dc.description.abstract | DELLA proteins are transcriptional regulators present in all land plants which have been shown to modulate the activity of over 100 transcription factors in Arabidopsis, involved in multiple physiological and developmental processes. It has been proposed that DELLAs transduce environmental information to pre-wired transcriptional circuits because their stability is regulated by gibberellins (GAs), whose homeostasis largely depends on environmental signals. The ability of GAs to promote DELLA degradation coincides with the origin of vascular plants, but the presence of DELLAs in other land plants poses at least two questions: what regulatory properties have DELLAs provided to the behavior of transcriptional networks in land plants, and how has the recruitment of DELLAs by GA signaling affected this regulation. To address these issues, we have constructed gene co-expression networks of four different organisms within the green lineage with different properties regarding DELLAs: Arabidopsis thaliana and Solanum lycopersicum (both with GA-regulated DELLA proteins), Physcomitrella patens (with GA-independent DELLA proteins) and Chlamydomonas reinhardtii (a green alga without DELLA), and we have examined the relative evolution of the subnetworks containing the potential DELLA-dependent transcriptomes. Network analysis indicates a relative increase in parameters associated with the degree of interconnectivity in the DELLA-associated subnetworks of land plants, with a stronger effect in species with GA-regulated DELLA proteins. These results suggest that DELLAs may have played a role in the coordination of multiple transcriptional programs along evolution, and the function of DELLAs as regulatory ‘hubs’ became further consolidated after their recruitment by GA signaling in higher plants. | es |
dc.description.sponsorship | Ministerio de Economía, Industria y Competitividad BFU2016-80621-P, BIO2014-52425-P | es |
dc.description.sponsorship | Unión Europea H2020-MSCA-RISE-2014-644435 | es |
dc.description.sponsorship | Ministerio de Educación, Cultura y Deporte FPU14/01941, FPU15/01756 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Frontiers Media | es |
dc.relation.ispartof | Frontiers in Plant Science, 8, 626-1-626-11. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Gene co-expression networks | es |
dc.subject | Integrative molecular systems biology | es |
dc.subject | Evo-devo | es |
dc.subject | Transcriptional regulation | es |
dc.subject | Plant signaling | es |
dc.title | Evolutionary Analysis of DELLA-Associated Transcriptional Networks | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Ciencias de la Computación e Inteligencia Artificial | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular | es |
dc.relation.projectID | BFU2016-80621-P | es |
dc.relation.projectID | BIO2014-52425-P | es |
dc.relation.projectID | H2020-MSCA-RISE-2014-644435 | es |
dc.relation.projectID | FPU14/01941 | es |
dc.relation.projectID | FPU15/01756 | es |
dc.relation.publisherversion | http://dx.doi.org/10.3389/fpls.2017.00626 | es |
dc.identifier.doi | 10.3389/fpls.2017.00626 | es |
idus.format.extent | 11 p. | es |
dc.journaltitle | Frontiers in Plant Science | es |
dc.publication.volumen | 8 | es |
dc.publication.initialPage | 626-1 | es |
dc.publication.endPage | 626-11 | es |
dc.identifier.sisius | 21172426 | es |