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Artículo
Rules of tissue packing involving different cell types: human muscle organization
dc.creator | Sánchez Gutiérrez, Daniel | es |
dc.creator | Sáez Manzano, Aurora | es |
dc.creator | Gómez Gálvez, Pedro | es |
dc.creator | Paradas López, Carmen | es |
dc.creator | Escudero Cuadrado, Luis María | es |
dc.date.accessioned | 2017-03-29T11:54:45Z | |
dc.date.available | 2017-03-29T11:54:45Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Sánchez Gutiérrez, D., Sáez Manzano, A., Gómez Gálvez, P., Paradas López, C.. y Escudero Cuadrado, L.M. (2017). Rules of tissue packing involving different cell types: human muscle organization. Scientific Reports, 7, 40444. | |
dc.identifier.issn | 2045-2322 | es |
dc.identifier.uri | http://hdl.handle.net/11441/56536 | |
dc.description.abstract | Natural packed tissues are assembled as tessellations of polygonal cells. These include skeletal muscles and epithelial sheets. Skeletal muscles appear as a mosaic composed of two different types of cells: the “slow” and “fast” fibres. Their relative distribution is important for the muscle function but little is known about how the fibre arrangement is established and maintained. In this work we capture the organizational pattern in two different healthy muscles: biceps brachii and quadriceps. Here we show that the biceps brachii muscle presents a particular arrangement, based on the different sizes of slow and fast fibres. By contrast, in the quadriceps muscle an unbiased distribution exists. Our results indicate that the relative size of each cellular type imposes an intrinsic organization into natural tessellations. These findings establish a new framework for the analysis of any packed tissue where two or more cell types exist. | es |
dc.description.sponsorship | España, Gobierno BFU2011-25734 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Nature Publishing Group | es |
dc.relation.ispartof | Scientific Reports, 7, 40444. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.title | Rules of tissue packing involving different cell types: human muscle organization | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Biología Celular | es |
dc.relation.projectID | BFU2011-25734 | es |
dc.relation.publisherversion | http://dx.doi.org/10.1038/srep40444 | es |
dc.identifier.doi | 10.1038/srep40444 | es |
idus.format.extent | 15 p. | es |
dc.journaltitle | Scientific Reports | es |
dc.publication.issue | 7 | es |
dc.publication.initialPage | 40444 | es |
dc.contributor.funder | Gobierno de España |