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dc.creatorSánchez Gutiérrez, Danieles
dc.creatorSáez Manzano, Auroraes
dc.creatorGómez Gálvez, Pedroes
dc.creatorParadas López, Carmen ‎es
dc.creatorEscudero Cuadrado, Luis Maríaes
dc.date.accessioned2017-03-29T11:54:45Z
dc.date.available2017-03-29T11:54:45Z
dc.date.issued2017
dc.identifier.citationSánchez Gutiérrez, D., Sáez Manzano, A., Gómez Gálvez, P., Paradas López, C.‎. y Escudero Cuadrado, L.M. (2017). Rules of tissue packing involving different cell types: human muscle organization. Scientific Reports, 7, 40444.
dc.identifier.issn2045-2322es
dc.identifier.urihttp://hdl.handle.net/11441/56536
dc.description.abstractNatural packed tissues are assembled as tessellations of polygonal cells. These include skeletal muscles and epithelial sheets. Skeletal muscles appear as a mosaic composed of two different types of cells: the “slow” and “fast” fibres. Their relative distribution is important for the muscle function but little is known about how the fibre arrangement is established and maintained. In this work we capture the organizational pattern in two different healthy muscles: biceps brachii and quadriceps. Here we show that the biceps brachii muscle presents a particular arrangement, based on the different sizes of slow and fast fibres. By contrast, in the quadriceps muscle an unbiased distribution exists. Our results indicate that the relative size of each cellular type imposes an intrinsic organization into natural tessellations. These findings establish a new framework for the analysis of any packed tissue where two or more cell types exist.es
dc.description.sponsorshipEspaña, Gobierno BFU2011-25734es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherNature Publishing Groupes
dc.relation.ispartofScientific Reports, 7, 40444.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleRules of tissue packing involving different cell types: human muscle organizationes
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Biología Celulares
dc.relation.projectIDBFU2011-25734es
dc.relation.publisherversionhttp://dx.doi.org/10.1038/srep40444es
dc.identifier.doi10.1038/srep40444es
idus.format.extent15 p.es
dc.journaltitleScientific Reportses
dc.publication.issue7es
dc.publication.initialPage40444es
dc.contributor.funderGobierno de España

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