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dc.creatorMoreno Amador, María de Lourdeses
dc.creatorRodríguez Herrera, Alfonsoes
dc.creatorSousa Martín, Carolinaes
dc.creatorComino Montilla, Isabel Maríaes
dc.date.accessioned2017-01-11T13:07:28Z
dc.date.available2017-01-11T13:07:28Z
dc.date.issued2017
dc.identifier.citationMoreno Amador, M.d.L., Rodríguez Herrera, A., Sousa Martín, C. y Comino Montilla, I.M. (2017). Biomarkers to monitor gluten-free diet compliance in celiac patients. Nutrients, 9 (1), 46.
dc.identifier.issn2072-6643es
dc.identifier.urihttp://hdl.handle.net/11441/52070
dc.description.abstractGluten-free diet (GFD) is the only treatment for celiac disease (CD). There is a general consensus that strict GFD adherence in CD patients leads to full clinical and histological remission accompanied by improvement in quality of life and reduced long-term complications. Despite the importance of monitoring the GFD, there are no clear guidelines for assessing the outcome or for exploring its adherence. Available methods are insufficiently accurate to identify occasional gluten exposure that may cause intestinal mucosal damage. Serological tests are highly sensitive and specific for diagnosis, but do not predict recovery and are not useful for follow-up. The use of serial endoscopies, it is invasive and impractical for frequent monitoring, and dietary interview can be subjective. Therefore, the detection of gluten immunogenic peptides (GIP) in feces and urine have been proposed as new non-invasive biomarkers to detect gluten intake and verify GFD compliance in CD patients. These simple immunoassays in human samples could overcome some key unresolved scientific and clinical problems in CD management. It is a significant advance that opens up new possibilities for the clinicians to evaluate the CD treatment, GFD compliance, and improvement in the quality of life of CD patientses
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherMDPIes
dc.relation.ispartofNutrients, 9 (1), 46.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectCeliac diseasees
dc.subjectGluten-free dietes
dc.subjectGluten immunogenic peptideses
dc.subjectFeceses
dc.subjectUrinees
dc.titleBiomarkers to monitor gluten-free diet compliance in celiac patientses
dc.typeinfo:eu-repo/semantics/articlees
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessrightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Microbiología y Parasitologíaes
dc.relation.publisherversion10.3390/nu9010046es
idus.format.extent14 p.es
dc.journaltitleNutrientses
dc.publication.volumen9es
dc.publication.issue1es
dc.publication.initialPage46es
dc.publication.endPagees

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