Effect of Distal Small Bowel Resection on Bile Salt Absorption in Caecum

Abstract

It is well known that surgical resection of the small bowel results in adaptive changes in the residual intestine (7, 13, 14). The entero-hepatic circulation of bile saits, which is responsible for main­ taining constant bile salt pool, is also impaired by intestinal resection. Bile salts are largely reabsorbed by an active trans­ port mechanism in the ileum (3, 8), and to a lesser extent by passive diffusion in the jejunum, caecum and colon