dc.creator | González Redondo, Pedro | |
dc.creator | Manunza, A. | |
dc.creator | Zidi, A. | |
dc.creator | Fernández Cabanás, Víctor Manuel | |
dc.creator | Carrizosa, J. | |
dc.creator | Belaifa, E. | |
dc.creator | Urrutia, B. | |
dc.creator | Polvillo Polo, Oliva | |
dc.creator | Amills, M. | |
dc.creator | Serradilla Manrique, Juan Manuel | |
dc.date.accessioned | 2015-10-13T18:16:02Z | |
dc.date.available | 2015-10-13T18:16:02Z | |
dc.date.issued | 2012 | |
dc.identifier.issn | 1918-1825 | es |
dc.identifier.uri | http://hdl.handle.net/11441/29395 | |
dc.description.abstract | Sterol regulatory element binding transcription factor 1 (SREBF1) regulates the expression of genes involved in
the biosynthesis of fatty acids and cholesterol. Herewith, we have sequenced the near-complete coding region and part of
the 3?UTR of the goat SREBF1 gene. In doing so, we have detected a missense c.353CT polymorphism causing a proline
to leucine substitution at position 118 (P118L). An association analysis with milk composition traits recorded in MurcianoGranadina
goats only revealed a statistical tendency linking SREBF1 genotype and milk omega-3 fatty acid content. The
lack of significant associations suggests that the P118L substitution does not involve a functional change. | es |
dc.description.abstract | Le facteur de transcription de´nomme´ Sterol regulatory element binding transcription factor 1 (SREBF1)
re´gule l’expression des ge`nes implique´s dans la biosynthe`se des acides gras et du choleste´rol. Dans cette e´tude, nous avons
se´quence´ la quasi-totalite´ de la re´gion codante et une partie du la re´gion 3?UTR du ge`ne SREBF1 de la che`vre. Ce travail,
nous a permis d’identifier un polymorphisme non-synonyme c.353CT causant la substitution d’une Proline en Leucine a`
la position 118. L’e´tude d’association avec la composition du lait enregistre´e en che`vres Murciano-Granadina, a re´ve´le´
seulement une tendance statistique reliant SREBF1 ge´notype et l’acide gras ome´ga-3 du lait. L’absence d’associations
significatives sugge`re que la substitution P118L n’implique pas un changement fonctionnel. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Agricultural Institute of Canada | es |
dc.relation.ispartof | Canadian Journal of Animal Science, 92, 167-173 | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Goat SREBF1 gene | es |
dc.subject | milk fat content and composition | es |
dc.subject | Ge`ne SREBF1de la che`vre | es |
dc.subject | composition de la matie`re grasse du lait | es |
dc.title | Short communication: An association analysis between one missense polymorphism at the SREBF1 gene and milk yield and composition traits in goats | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Ciencias Agroforestales | es |
dc.relation.publisherversion | doi:10.4141/CJAS2011-111 | es |
dc.relation.publisherversion | http://dx.doi.org/10.4141/cjas2011-111 | |
dc.identifier.doi | 10.4141/cjas2011-111 | |
dc.identifier.idus | https://idus.us.es/xmlui/handle/11441/29395 | |