dc.creator | Serrano Morales, José Manuel | es |
dc.creator | Álvarez Santaliestra, Noelia | es |
dc.creator | Sánchez González, María del Carmen | es |
dc.creator | Ballesteros Sánchez, Antonio | es |
dc.creator | Sánchez González, José María | es |
dc.date.accessioned | 2024-06-04T07:28:24Z | |
dc.date.available | 2024-06-04T07:28:24Z | |
dc.date.issued | 2024 | |
dc.identifier.citation | Serrano Morales, J.M., Álvarez Santaliestra, N., Sánchez González, M.d.C., Ballesteros Sánchez, A. y Sánchez González, J.M. (2024). Impact of Dyslipidemia on Tear Film and Meibomian Gland Dysfunction: A Cross-Sectional Study of the Interplay between Serum Lipid Profile and Ocular Surface Health. Journal of Ophthalmology, 2024, 7345270. https://doi.org/10.1155/2024/7345270. | |
dc.identifier.issn | 2090-004X (impreso) | es |
dc.identifier.issn | 2090-0058 (electrónico) | es |
dc.identifier.uri | https://hdl.handle.net/11441/159638 | |
dc.description.abstract | Purpose. To determine the relationship between dyslipidemia and dry eye disease (DED), as well as its influence on tear 6lm and meibomian glands. Methods. ,is cross-sectional study included 40 patients with a mean age of 35.2 ± 13.9 years without any history of dyslipidemia. DED and serum lipid profile were evaluated after 8 hours of fasting. Patients were classified according to serum lipid levels with the following cut-off values: total cholesterol (TC) (200 mg/dl), high-density lipoprotein (HDL) (40 mg/dl),
low-density lipoprotein (LDL) (130 mg/dl), and triglycerides (TG) (150 mg/dl). The relationship between serum lipid levels and DED was analyzed with the following variables: dry eye questionnaire-5 (DEQ-5), 6rst (F-NIBUT) and average (A-NIBUT) noninvasive breakup time, tear meniscus height (TMH), lipid layer grade (LLG), conjunctival bulbar redness (CBR), and upper (U-LAMG) and lower (L-LAMG) loss area of meibomian glands. Results. Regarding tear 6lm, patients with elevated TC and LDL levels reported significantly higher DEQ-5 scores and TMH (P < 0.05), while those with lower HDL levels showed significantly higher LLG (p < 0.05). Regarding MGD, patients with elevated TC, LDL, and TG, as well as lower HDL levels showed significantly higher L-LAMG (p < 0.05). HDL was correlated with LLG (p < 0.05), while TC was correlated with TMH (p < 0.05) and L-LAMG (p < 0.05), respectively. Conclusions. Disorders in TC, HDL, LDL, and TG levels were associated with DED, having an impact on the tear film and meibomian glands, specifically in DEQ-5 scores, LLG, and L-LAMG. | es |
dc.format | application/pdf | es |
dc.format.extent | 8 p. | es |
dc.language.iso | eng | es |
dc.publisher | Hindawi Publishing Corp | es |
dc.relation.ispartof | Journal of Ophthalmology, 2024, 7345270. | |
dc.rights | Attribution 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.title | Impact of Dyslipidemia on Tear Film and Meibomian Gland Dysfunction: A Cross-Sectional Study of the Interplay between Serum Lipid Profile and Ocular Surface Health | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Física de la Materia Condensada | es |
dc.relation.publisherversion | https://doi.org/10.1155/2024/7345270 | es |
dc.identifier.doi | 10.1155/2024/7345270 | es |
dc.journaltitle | Journal of Ophthalmology | es |
dc.publication.volumen | 2024 | es |
dc.publication.initialPage | 7345270 | es |