dc.creator | Ballesteros Sánchez, Antonio | es |
dc.creator | Sánchez González, José María | es |
dc.creator | Gutiérrez Ortega, Ramón | es |
dc.creator | Gargallo Martínez, Beatriz | es |
dc.date.accessioned | 2024-06-03T13:23:08Z | |
dc.date.available | 2024-06-03T13:23:08Z | |
dc.date.issued | 2024-03-11 | |
dc.identifier.citation | Ballesteros Sánchez, A., Sánchez González, J.M., Gutiérrez Ortega, R. y Gargallo Martínez, B. (2024). Diamond Bur Microblepharoexfoliation Combined with Intense Pulse Light and Meibomian Gland Expression for Evaporative Dry Eye: A Short-term Controlled Clinical Trial.. Ophthalmology and Therapy, 13 (5), 1223-1237. https://doi.org/10.1007/s40123-024-00919-w. | |
dc.identifier.issn | 2193-6528 | es |
dc.identifier.issn | 2193-8245 | es |
dc.identifier.uri | https://hdl.handle.net/11441/159619 | |
dc.description.abstract | Introduction: To assess the efficacy and safety
of the combination of microblepharoexfoliation (MBE), intense pulse light (IPL) and meibomian gland expression (MGX) for treatment
of meibomian gland dysfunction (MGD).
Methods: This was a prospective, parallel-control trial conducted from April 2022 to January
2023. Participants were assigned to receive
either three sessions of MBE-IPL-MGX treatment and home-based therapy (treatment
group) or home-based therapy alone (control
group). Outcome measures were assessed at
baseline and after 2-month follow-up.
Results: Seventy eyes of 70 patients were
enrolled. MBE-IPL-MGX treatment achieved
better improvements than home-based therapy
in ocular surface disease index (OSDI) and
symptom assessment in dry eye (SANDE) scores,
noninvasive tear film break-up time (NIBUT),
lipid layer grade (LLG), loss area meibomian
gland (LAMG) and meibomian gland yielding
secretion score (MGYSS). The mean differences
between the two groups were as follows: OSDI (–
11.23 ± 4.68 points, P \0.001), SANDE (–
24.63 ± 13.41 points, P \0.001), NIBUT
(1.3 ± 1.57 s, P = 0.033), LLG (0.4 ± 0.04
points, P = 0.003), LAMG (– 2.85 ± 1.69%,
P = 0.023) and MGYSS (7.5 ± 2.32 points,
P \ 0.001). In addition, the increment (D) of
MGYSS after MBE-IPL-MGX treatment was significantly higher in MGD grades 2 and 3 (all
P \ 0.001).
Conclusions: MBE-IPL-MGX treatment is an
effective and well-tolerated procedure that
improves dry eye symptoms and signs as well as
meibomian gland secretions in patients with
MGD. In addition, this treatment is recommended for MGD grades 2 and 3. | es |
dc.format | application/pdf | es |
dc.format.extent | 15 | es |
dc.language.iso | eng | es |
dc.publisher | Springer Science and Business Media LLC | es |
dc.relation.ispartof | Ophthalmology and Therapy, 13 (5), 1223-1237. | |
dc.rights | Atribución-NoComercial 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject | Microblepharoexfoliation | es |
dc.subject | Intense pulse light | es |
dc.subject | Meibomian gland expression | es |
dc.subject | Meibomian gland dysfunction | es |
dc.subject | Dry eye disease | es |
dc.title | Diamond Bur Microblepharoexfoliation Combined with Intense Pulse Light and Meibomian Gland Expression for Evaporative Dry Eye: A Short-term Controlled Clinical Trial. | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Física de la Materia Condensada | es |
dc.relation.publisherversion | https://doi.org/10.1007/s40123-024-00919-w | es |
dc.identifier.doi | 10.1007/s40123-024-00919-w | es |
dc.contributor.group | Universidad de Sevilla. CTS1040: Ciencias de la Visión | es |
dc.journaltitle | Ophthalmology and Therapy | es |
dc.publication.volumen | 13 | es |
dc.publication.issue | 5 | es |
dc.publication.initialPage | 1223 | es |
dc.publication.endPage | 1237 | es |