Artículo
Diamond Bur Microblepharoexfoliation Combined with Intense Pulse Light and Meibomian Gland Expression for Evaporative Dry Eye: A Short-term Controlled Clinical Trial.
Autor/es | Ballesteros Sánchez, Antonio
Sánchez González, José María ![]() ![]() ![]() ![]() ![]() ![]() ![]() Gutiérrez Ortega, Ramón Gargallo Martínez, Beatriz ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Departamento | Universidad de Sevilla. Departamento de Física de la Materia Condensada |
Fecha de publicación | 2024-03-11 |
Fecha de depósito | 2024-06-03 |
Publicado en |
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Resumen | Introduction: To assess the efficacy and safety
of the combination of microblepharoexfoliation (MBE), intense pulse light (IPL) and meibomian gland expression (MGX) for treatment
of meibomian gland dysfunction (MGD).
Methods: ... Introduction: To assess the efficacy and safety of the combination of microblepharoexfoliation (MBE), intense pulse light (IPL) and meibomian gland expression (MGX) for treatment of meibomian gland dysfunction (MGD). Methods: This was a prospective, parallel-control trial conducted from April 2022 to January 2023. Participants were assigned to receive either three sessions of MBE-IPL-MGX treatment and home-based therapy (treatment group) or home-based therapy alone (control group). Outcome measures were assessed at baseline and after 2-month follow-up. Results: Seventy eyes of 70 patients were enrolled. MBE-IPL-MGX treatment achieved better improvements than home-based therapy in ocular surface disease index (OSDI) and symptom assessment in dry eye (SANDE) scores, noninvasive tear film break-up time (NIBUT), lipid layer grade (LLG), loss area meibomian gland (LAMG) and meibomian gland yielding secretion score (MGYSS). The mean differences between the two groups were as follows: OSDI (– 11.23 ± 4.68 points, P \0.001), SANDE (– 24.63 ± 13.41 points, P \0.001), NIBUT (1.3 ± 1.57 s, P = 0.033), LLG (0.4 ± 0.04 points, P = 0.003), LAMG (– 2.85 ± 1.69%, P = 0.023) and MGYSS (7.5 ± 2.32 points, P \ 0.001). In addition, the increment (D) of MGYSS after MBE-IPL-MGX treatment was significantly higher in MGD grades 2 and 3 (all P \ 0.001). Conclusions: MBE-IPL-MGX treatment is an effective and well-tolerated procedure that improves dry eye symptoms and signs as well as meibomian gland secretions in patients with MGD. In addition, this treatment is recommended for MGD grades 2 and 3. |
Cita | Ballesteros Sánchez, A., Sánchez González, J.M., Gutiérrez Ortega, R. y Gargallo Martínez, B. (2024). Diamond Bur Microblepharoexfoliation Combined with Intense Pulse Light and Meibomian Gland Expression for Evaporative Dry Eye: A Short-term Controlled Clinical Trial.. Ophthalmology and Therapy, 13 (5), 1223-1237. https://doi.org/10.1007/s40123-024-00919-w. |
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