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Use of Polymer Inclusion Membranes (PIMs) as Support for Electromembrane Extraction of Non-steroidal Anti-inflammatory Drugs and Highly Polar Acidic Drugs

dc.creatorRomán Hidalgo, Cristinaes
dc.creatorMartín Valero, María Jesúses
dc.creatorFernández Torres, Rutes
dc.creatorBello López, Miguel Ángeles
dc.date.accessioned2024-01-10T18:02:43Z
dc.date.available2024-01-10T18:02:43Z
dc.date.issued2018
dc.identifier.citationRomán Hidalgo, C., Martín Valero, M.J., Fernández Torres, R. y Bello López, M.Á. (2018). Use of Polymer Inclusion Membranes (PIMs) as Support for Electromembrane Extraction of Non-steroidal Anti-inflammatory Drugs and Highly Polar Acidic Drugs. Talanta, 179, 601-607. https://doi.org/10.1016/j.talanta.2017.11.066.
dc.identifier.issn0039-9140es
dc.identifier.issn1873-3573es
dc.identifier.urihttps://hdl.handle.net/11441/153190
dc.description.abstractThe use of polymer inclusion membranes (PIMs) as support of 1-octanol liquid membrane in electromembrane extraction (EME) procedure is proposed. Synthesis of PIMs were optimized to a composition of 29% (w/w) of cellulose triacetate as base polymer and 71% (w/w) of Aliquat®336 as cationic carrier. Flat PIMs of 25 µm thickness and 6 mm diameter were used. EME protocol was implemented for the simultaneous extraction of four non-steroidal anti-inflammatory drugs (NSAIDs) (salicylic acid, ketoprofen, naproxen and ibuprofen) and four highly polar acidic drugs (anthranilic acid, nicotinic acid, amoxicillin and hippuric acid). Posterior HPLC separation of the extracted analytes was developed with diode array detection. Recoveries in the 81–34% range were obtained. EME procedure was applied to human urine samples.es
dc.description.sponsorshipMinisterio de Educación y Ciencia TM2015-67902-C-1-Pes
dc.formatapplication/pdfes
dc.format.extent23 p.es
dc.language.isoenges
dc.publisherElsevieres
dc.relation.ispartofTalanta, 179, 601-607.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectElectromembrane extractiones
dc.subjectNon-steroidal anti-inflammatory drugses
dc.subjectPIMes
dc.subjectPolar drugses
dc.subjectPolymer inclusion membraneses
dc.titleUse of Polymer Inclusion Membranes (PIMs) as Support for Electromembrane Extraction of Non-steroidal Anti-inflammatory Drugs and Highly Polar Acidic Drugses
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/acceptedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Química Analíticaes
dc.relation.projectIDTM2015-67902-C-1-Pes
dc.relation.publisherversionhttps://doi.org/10.1016/j.talanta.2017.11.066es
dc.identifier.doi10.1016/j.talanta.2017.11.066es
dc.journaltitleTalantaes
dc.publication.volumen179es
dc.publication.initialPage601es
dc.publication.endPage607es
dc.contributor.funderMinisterio de Educación y Ciencia (MEC). Españaes
dc.description.awardwinningPremio Mensual Publicación Científica Destacada de la US. Facultad de Química

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