dc.creator | Granja-Domínguez, Anabel | es |
dc.creator | Hochsprung, Anja | es |
dc.creator | Luque Moreno, Carlos | es |
dc.creator | Magni, Eleonora | es |
dc.creator | Escudero-Uribe, Shahid | es |
dc.creator | Izquierdo-Ayuso, Guillermo | es |
dc.creator | Heredia Rizo, Alberto Marcos | es |
dc.date.accessioned | 2023-07-05T13:49:33Z | |
dc.date.available | 2023-07-05T13:49:33Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Granja-Domínguez, A., Hochsprung, A., Luque Moreno, C., Magni, E., Escudero-Uribe, S., Izquierdo-Ayuso, G. y Heredia Rizo, A.M. (2022). Effects of pulsed electromagnetic field therapy on fatigue, walking performance, depression, and quality of life in adults with multiple sclerosis: a randomized placebo-controlled trial. BRAZILIAN JOURNAL OF PHYSICAL THERAPY (1413-3555 / 1809-9246). https://doi.org/10.1016/j.bjpt.2022.100449. | |
dc.identifier.issn | 1413-3555 | es |
dc.identifier.uri | https://hdl.handle.net/11441/147746 | |
dc.description.abstract | Background: Multiple sclerosis has a great disability burden. Management of the disease is complex, and patients often seek new conservative approaches.
Objective: To investigate the effect of low-frequency pulsed electromagnetic field (PEMF) therapy, compared to placebo, on the level of fatigue, walking performance, symptoms of depression, and quality of life (QOL) in patients with relapsing-remitting multiple sclerosis (RRMS).
Methods: Forty-four adults with RRMS and minimal to significant disability were randomly
assigned to a 4-week protocol using a PEMF or a placebo whole-body mat. The PEMF group were
initially treated with 15Hz frequency, gradually increased to 30Hz (intensity between 25-35mT).
The primary outcome was fatigue, assessed with the Fatigue Severity Scale (FSS) and the Modified Fatigue Impact Scale (MFIS). Secondary measures included walking function (GAITRite system and Timed 25-Foot Walk test), the Beck Depression Inventory-II, and the Multiple Sclerosis
International Quality of Life Questionnaire. Data were collected at baseline, after intervention,
and at 3-months post-intervention (follow-up).
Results: There were no differences between groups for changes in fatigue symptoms from baseline to end of intervention (mean and 95% confidence interval FSS: -0.6, 95%CI: -1.3, 0.1; MFIS: -5.4, 95% CI: -15.1, 4.4) or at follow-up (FSS: -0.6, 95% CI: -1.4, 0.2; MFIS: -2.1, 95% CI: -10.9,
6.8). Similarly, both groups did not differ for any of the secondary outcomes at post-intervention
or follow-up.
Conclusions: Low-frequency PEMF therapy is no more effective than placebo to produce changes
in fatigue, gait performance, severity of depression, and QOL in people with RRMS and minimal
to significant disability. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.relation.ispartof | BRAZILIAN JOURNAL OF PHYSICAL THERAPY (1413-3555 / 1809-9246). | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Fatigue | es |
dc.subject | Magnetic field therapy | es |
dc.subject | Neurologic gait disorder | es |
dc.subject | Placebo effect | es |
dc.subject | Quality of life | es |
dc.subject | Relapsing-remitting multiple sclerosis | es |
dc.title | Effects of pulsed electromagnetic field therapy on fatigue, walking performance, depression, and quality of life in adults with multiple sclerosis: a randomized placebo-controlled trial | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Fisioterapia | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Enfermería | es |
dc.identifier.doi | 10.1016/j.bjpt.2022.100449 | es |
dc.journaltitle | BRAZILIAN JOURNAL OF PHYSICAL THERAPY (1413-3555 / 1809-9246) | es |