dc.creator | Jiménez Sánchez, María del Carmen | es |
dc.creator | Cabanillas Balsera, Daniel | es |
dc.creator | Areal Quecuty, Victoria | es |
dc.creator | Velasco Ortega, Eugenio | es |
dc.creator | Martín González, Jenifer | es |
dc.creator | Segura Egea, Juan José | es |
dc.date.accessioned | 2023-05-03T06:41:47Z | |
dc.date.available | 2023-05-03T06:41:47Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Jiménez Sánchez, M.d.C., Cabanillas Balsera, D., Areal Quecuty, V., Velasco Ortega, E., Martín González, J. y Segura Egea, J.J. (2020). Cardiovascular diseases and apical periodontitis: association not always implies causality. Medicina oral, patología oral y cirugía bucal, 25 (5), e1-e8. https://doi.org/10.4317/medoral.23665. | |
dc.identifier.issn | 1698-4447 | es |
dc.identifier.issn | 1698-6946 | es |
dc.identifier.uri | https://hdl.handle.net/11441/144964 | |
dc.description.abstract | Background: Several studies published in the last two decades have found an association between the prevalence
of apical periodontitis (AP) or root canal treatment (RCT) and cardiovascular diseases (CVDs). However, the
demonstration of association does not prove by itself the existence of a cause–effect relationship. Two diseases
can appear as statistically related without any of them directly affecting the values of the other, resulting in a
non-causal relationship. The aim of this narrative review is to summarize the current state of knowledge regarding
the association between AP and CVDs, analysing it according to the Hill’s causality criteria.
Materials and Methods: Epidemiological studies carried out on the association between CVDs and AP or RCT published
in English until 8 December 2019 were identified. Forty-four articles were selected and its results were analysed.
Results: Numerous cross-sectional epidemiological studies have found significant relationship between CVDs and
AP. The odds ratio values range 1.6 - 5.4. However, other studies have not found significant association. Respect
to RCT, some studies found correlation, but others found no association or even found that RCT is a protective
factor against CVDs.
Conclusions: The results are inconsistent and a causal relationship between CVDS and endodontic disease cannot
be stablished. The risk factors common to both diseases can act as confounding factors, biasing the results. To reach
definitive conclusions about the type of association (causal or non-causal) between both diseases, longitudinal epidemiological
studies must be carried out to establish the temporal relationship and the dose-response gradient. | es |
dc.format | application/pdf | es |
dc.format.extent | 8 | es |
dc.language.iso | eng | es |
dc.publisher | Medicina Oral S.L. | es |
dc.relation.ispartof | Medicina oral, patología oral y cirugía bucal, 25 (5), e1-e8. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Apical periodontitis | es |
dc.subject | Atherosclerosis | es |
dc.subject | Cardiovascular disease | es |
dc.subject | Coronary heart disease | es |
dc.subject | Endodontic medicine | es |
dc.subject | Root canal treatment | es |
dc.title | Cardiovascular diseases and apical periodontitis: association not always implies causality | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Estomatología | es |
dc.identifier.doi | 10.4317/medoral.23665 | es |
dc.contributor.group | Universidad de Sevilla. CTS941: Patología Dentaria, Operatoria Dental y Endodoncia | es |
dc.journaltitle | Medicina oral, patología oral y cirugía bucal | es |
dc.publication.volumen | 25 | es |
dc.publication.issue | 5 | es |
dc.publication.initialPage | e1 | es |
dc.publication.endPage | e8 | es |