dc.creator | Cruz Chamorro, Iván | es |
dc.creator | Santos Sánchez, Guillermo | es |
dc.creator | Álvarez-López, Ana Isabel | es |
dc.creator | Pedroche, Justo | es |
dc.creator | Lardone, Patricia Judith | es |
dc.creator | Arnoldi, Anna | es |
dc.creator | Lammi, Carmen | es |
dc.creator | Carrillo Vico, Antonio | es |
dc.date.accessioned | 2023-04-24T10:12:53Z | |
dc.date.available | 2023-04-24T10:12:53Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Cruz Chamorro, I., Santos Sánchez, G., Álvarez-López, A.I., Pedroche, J., Lardone, P.J., Arnoldi, A.,...,Carrillo Vico, A. (2023). Pleiotropic biological effects of Lupinus spp. protein hydrolysates. TRENDS IN FOOD SCIENCE & TECHNOLOGY, 133, 244-266. https://doi.org/10.1016/j.tifs.2023.02.011. | |
dc.identifier.issn | 0924-2244 | es |
dc.identifier.uri | https://hdl.handle.net/11441/144791 | |
dc.description.abstract | Background: Over the last two decades, the demand for meat-free food has increased for health, environmental,
and animal welfare reasons. Thus, research on the value of vegetable compounds as beneficial agents for human
health has gained much attention. In particular, great interest has been shown in protein hydrolysation since this
food technology facilitates the release of encrypted peptides with biological activities. In this sense, during the
last 10 years, the biological activities of Lupinus spp. protein hydrolysates (LPHs) have been extensively studied.
Scope and approach: The aim of this review is to address all studies (in silico, in vitro, and in vivo) in which the
biological activities (antioxidant, anti-inflammatory, etc.) of LPHs were described, both the whole hydrolysate
and the derived peptides. Moreover, the physicochemical characteristics of LPH peptides are evaluated, and
challenges and future perspectives for their fast application have been discussed.
Key findings and conclusions: LPHs exert many important biological effects in both the in vitro and in vivo systems.
The main activities of LPHs described are antioxidant, immunomodulatory, hypotensive, hypoglycemic, and
hypolipidemic. These findings point to LPHs as a possible new nutraceutical for human health, capable of preventing
or treating some chronic diseases such as diabetes, dyslipidemia, and atherosclerosis. Finally, the
development of a new generation of nanonutraceuticals to improve the metabolic stability and bioactivity of
LPHs has been discussed. | es |
dc.description.sponsorship | Ministerio de Economía y Competitividad. España | es |
dc.format | application/pdf | es |
dc.format.extent | 23 p. | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.relation.ispartof | TRENDS IN FOOD SCIENCE & TECHNOLOGY, 133, 244-266. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Hydrolysates | es |
dc.subject | Bioactive compounds | es |
dc.subject | Interleukin | es |
dc.subject | Oxidative stress | es |
dc.subject | LDL-R | es |
dc.subject | Nutraceuticals | es |
dc.title | Pleiotropic biological effects of Lupinus spp. protein hydrolysates | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Bioquímica Médica y Biología Molecular e Inmunología | es |
dc.relation.projectID | AGL2012-40247-C02-01 | es |
dc.relation.projectID | AGL2012- 40247-C02-02 | es |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S0924224423000626?via%3Dihub | es |
dc.identifier.doi | 10.1016/j.tifs.2023.02.011 | es |
dc.journaltitle | TRENDS IN FOOD SCIENCE & TECHNOLOGY | es |
dc.publication.volumen | 133 | es |
dc.publication.initialPage | 244 | es |
dc.publication.endPage | 266 | es |
dc.description.awardwinning | Premio Mensual Publicación Científica Destacada de la US. Facultad de Medicina | |