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Artículo
Generation of a human iPS cell line (CABi003-A) from a patient with age-related macular degeneration carrying the CFH Y402H polymorphism
Autor/es | García Delgado, Ana Belén
Calado, Sofía M. Valdés Sánchez, Lourdes Montero Sánchez, Adoración Ponte-Zuñiga, Beatriz De la Cerda, Berta Bhattacharya, Shom Shanker Díaz Corrales, Francisco Javier |
Departamento | Universidad de Sevilla. Departamento de Farmacia y Tecnología Farmacéutica Universidad de Sevilla. Departamento de Cirugía |
Fecha de publicación | 2019 |
Fecha de depósito | 2023-02-06 |
Publicado en |
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Resumen | Age-related macular degeneration (AMD) is the leading cause of adult blindness in developed countries and is characterized by progressive degeneration of the
macula, the central region of the retina. A human induced ... Age-related macular degeneration (AMD) is the leading cause of adult blindness in developed countries and is characterized by progressive degeneration of the macula, the central region of the retina. A human induced pluripotent stem cell (hiPSC) line was derived from peripheral blood mononuclear cells (PBMCs) from a patient with a clinical diagnosis of dry AMD carrying the CFH Y402H polymorphism. Sendai virus was using for reprogramming and the pluripotent and differ- entiation capacity of the cells were assessed by immunocytochemistry and RT-PCR. |
Agencias financiadoras | Instituto de Salud Carlos III (ISCIII). España European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER) |
Identificador del proyecto | ISCIII Miguel Servet-I 2015
FEDER CP 15/00071 |
Cita | García Delgado, A.B., Calado, S.M., Valdés Sánchez, L., Montero Sánchez, A., Ponte-Zuñiga, B., De la Cerda, B.,...,Díaz Corrales, F.J. (2019). Generation of a human iPS cell line (CABi003-A) from a patient with age-related macular degeneration carrying the CFH Y402H polymorphism. Stem Cell Research, 38, 101473. https://doi.org/10.1016/j.scr.2019.101473. |
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1-s2.0-S1873506119301035-main.pdf | 1.277Mb | [PDF] | Ver/ | |