Artículo
Synchronous occurrence of IgG4-related sialadenitis and ductal carcinoma of the parotid gland a case report
Autor/es | Rollón Mayordomo, Ángel
![]() ![]() ![]() ![]() ![]() ![]() Avellaneda Camarena, Ana Gutiérrez Domingo, Álvaro Martínez Carapeto, Elena Infante Cossío, Pedro Antonio ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Departamento | Universidad de Sevilla. Departamento de Cirugía |
Fecha de publicación | 2021-06 |
Fecha de depósito | 2023-01-12 |
Publicado en |
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Resumen | Immunoglobulin G4-related disease (IgG4-RD) is a rare chronic systemic inflammatory pathology that poses a diagnostic challenge since it can simulate malignancy when it affects a salivary gland as a mass-like lesion. Here, ... Immunoglobulin G4-related disease (IgG4-RD) is a rare chronic systemic inflammatory pathology that poses a diagnostic challenge since it can simulate malignancy when it affects a salivary gland as a mass-like lesion. Here, the authors report an unusual clinical case of a 42-year-old man who presented with a painless, slow-growing swelling located in the right parotid gland with a 12-month evolution. Based on imaging tests and open biopsy, a diagnosis of chronic parotitis was presumed and oral methylprednisolone was prescribed. Due to poor response to medication, a total parotidectomy preserving the facial nerve was performed. The final pathology described a unilateral IgG4-related sialadenitis (IgG4-RS) in the parotid gland in combination with a poorly differentiated multifocal ductal carcinoma. The postoperative course was uneventful except for a temporary facial paresis (grade III according to the House-Brackmann classification system) that resolved completely within 5 months. There were no systemic manifestations on the whole-body 18F-FDG PET/CT. Adjuvant radiotherapy was administered without complications. Twenty-four months follow-up after surgery showed no recurrence or evidence of systemic involvement. This clinical report highlights the importance of considering the synchronous occurrence of a carcinoma underlying an isolated parotid gland mass in the context of IgG4-RS, especially if there is no response to prior steroid medication. |
Cita | Rollón Mayordomo, Á., Avellaneda Camarena, A., Gutiérrez Domingo, Á., Martínez Carapeto, E. y Infante Cossío, P.A. (2021). Synchronous occurrence of IgG4-related sialadenitis and ductal carcinoma of the parotid gland a case report. Gland Surgery, 10 (6), 2069-2075. https://doi.org/10.21037/gs-21-90. |
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